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bix02188

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  • Inhibitors & Agonists
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BIX02188
T1744334949-59-6
BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD.
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7-10 days
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(E/Z)-BIX02188
334949-59-6
T63241094614-84-2
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1 2, JNK2, and ERK2.
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