cbz-n-amido-peg20-acid

Cbz-N-amido-PEG20-acid is a PEG-based linker for PROTACs [proteolysis-targeting chimeras] that connects two critical ligands essential for the formation of PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

20-(tert-Butoxy)-20-oxoicosanoic acid is an alkyl-chain-based, non-cleavable PROTAC linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker incorporating biotin for labeling, making it a versatile tool in PROTAC synthesis[1].

N-(Amino-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group, primarily used in PROTAC synthesis [1].

N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Fmoc-N-PEG24-acid is a PEG-based linker for PROTACs, crucial for connecting two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based linker widely used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-(Propanoic acid)-N-bis(m-PEG12) is a polyethylene glycol (PEG) based linker used in PROTACs synthesis [1].

Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derivative of Estrone that specifically binds to estrogen receptor α (ERα). With a linker, it complexes with the cIAP1 ligand Bestatin, forming SNIPER[1].

N-DBCO-N-bis(PEG2-C2-acid) is a polyethylene glycol (PEG) linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Cbz-NH-PEG8-C2-acid is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-N-amido-PEG2-alcohol is a PEG-based linker for PROTACs [which joins two essential ligands], crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis [1].

Boc-N-Amido-PEG5-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker designed for PROTAC synthesis[1].

N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

N-(Biotin-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of PROTACs[1].

Cbz-N-PEG10-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-N-amido-PEG-CH2COOH (MW 5000), a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

Cbz-NH-PEG24-C2-acid is a PEG-based linker for PROTACs that enables selective protein degradation by linking two essential ligands, crucial for forming PROTAC molecules, and leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used in the development of antibody-drug conjugates (ADC).

N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEGylated PROTAC linker with azide, fluorescein, and carboxylic acid functional groups.

N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

N-Me-N-bis(PEG4-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-(m-PEG4)-3,3-Dimethyl-3H-indole-N'-(acid-PEG3)-benzothiazole is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

Mal-amido-PEG12-acid is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-amido-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Fmoc-N-amido-PEG20-acid is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

Cbz-NH-PEG2-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two key ligands essential for PROTAC molecule formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-(m-PEG8-amido)-hexanoic acid is a polyethylene glycol (PEG)-based linker used in synthesizing proteolysis targeting chimeras (PROTACs) [1].

1-Cbz-azetidine-3-carboxylic acid (catalog number: T66609, CAS number: 97628-92-7) is a valuable organic compound for life sciences research.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a polyethylene glycol (PEG)-based linker frequently used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Boc-N-bis(PEG2-acid) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-amido-PEG24-acid is a PEG-based linker for PROTACs that joins two essential ligands, critical for the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-N-Amido-PEG3-azide is a PEG-based linker used in PROTACs that joins two essential ligands, facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl ether-based linker suitable for PROTAC synthesis [1].