cimigenol

Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87μM) and A-549 (12.16 μM

25-O-Acetyl-7,8-didehydro-cimigenol-3-O-β-D-xylopyranoside is a cycloartane triterpenoid isolated from Cimicifuga acerina [1].

Cimigenol-3-one is a natural product from Calophyllum inophyllum.

7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression.

25-O-methylcimigenol-3-O-beta-D-xylopyranoside is a natural product from Actaea asiatica.

25-Anhydrocimigenol 3-O-beta-D-xyloside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

25-O-ethylcimigenol-3-O-beta-D-xylopyranoside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.