ent-3b-tigloyloxykaur-16-en-19-oic acid

Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b negatively regulates p85 in an independent proteolytic manner, and participates in the recruitment of p85 to CD28 and T cell antigen receptor ζ through its E3 ubiquitin ligase activity. Inhibition of PI3K inhibits the enhancement of Cblb-/ -T cell activation.

Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.

4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system.

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid has hepatoprotective activity, antiamnesic activity, enhances cognitive effects, and can be used to lower blood pressure sugar.

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical pa

5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER is a useful organic compound for research related to life sciences. The catalog number is T9829 and the CAS number is 104685-76-9.

4-(METHYLAMINO)-3-NITROBENZOIC ACID (4-Methylamino-3-nitrobenzoic acid) is an intermediate that is a yellow solid. It is mainly used in the synthesis of dabigatranate intermediates.

3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyrosine metabolism. 3-Hydroxyphenylace

(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.

Compound Fr14428 is a useful organic compound for research related to life sciences. The catalog number is Fr14428 and the CAS number is 2458-12-0.

6-Bromoindole-3-carboxylic acid (ZINC2547985) is a marine derived natural products found in Pseudosuberites hyalinus.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

(2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid is a chemical synthesis intermediate.

3-Amino-5-Hydroxybenzoic Acid (3-amino-5-hydroxy-benzoic acid) is a marine derived natural products found in Salinispora arenicola.

(6Z)-7-Phenyl-7-(3-Pyridinyl)-6-Heptenoic Acid is a derivative of 7-Phenyl-7-(3-Pyridyl) -6-Heptenoic Acid that can be used in biological research.

3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patients that inhibits the formation of Aβ42 oligomers.

5,6-dibromo-1H-indole-3-carboxylic acid (5,6-dibromo-1H-indole-3-carboxylicAcid) is a marine derived natural products found in Smenospongia sp.

3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid (DCPPA) is an ASIC3 inhibitor that effectively blocks ASIC3-mediated pain and inflammation. It has been shown to have potential applications in the treatment of other diseases such as stroke, epilepsy and cancer.

(E)-3-(Naphth-1-yl)acrylic acid (3-(1-Naphthyl)acrylic acid) is a biochemical reagent that can be used to synthesize a variety of compounds and participate in many reactions in the body.

3-Methyl-2-nitrobenzoic acid is in agricultural chemicals such asWithPreparation in be used as intermediate.

6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) is a marine derived natural products found in Pseudosuberites hyalinus.

2-Methyl-2H-indazole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is Fr21265 and the CAS number is 34252-44-3.

(4R)-3-[2-(4-chlorophenoxy)-2-methylpropanoyl]-1,3-thiazolidine-4-carboxylic acid can be used in research in the fields of chemistry and life sciences.

3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.

DL-Indole-3-lactic acid is a reactant for the preparation of antibacterial agents.

B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used for cancer or tumour research.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.

Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.

Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) (3-methoxy-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)benzamide) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including diabetes, cardiovascular disease, bloo

sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate is an organosulfur compound. It has been used as a model compound to study the effects of sulfur-containing compounds on enzymatic activities and metabolic pathways. It has also been used to study the effects of sulfur-containing compounds on the regulation of bacterial growth and gene expression.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.

b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.

Ellagic acid 3-O-α-L-rhamnopyranoside is a natural product found in the tuberous roots of Potentilla anserina.

(3E)-4-(1H-indol-3-yl)but-3-en-2-one ((E)-4-(1H-indol-3-yl)but-3-en-2-one) is a marine derived natural products found in Tedania (Tedania) ignis.

2-(Acetyloxy)-3-Methylbenzoic Acid is used in qHTS Assay for Inhibitors of hydroxysteroid (17-beta) dehydrogenase 4, HSD17B4 with activity value of 19.95 μM

1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) is a plant-physiologically tolerable salt radical or any desired ester radical.

3-Bromo-6-chloro-2-pyridinecarboxylic acid is a biochemical reagent that can be used to synthesize other compounds.

3-Feruloyl-4-caffeoylquinic acid is a chlorogenic acid isomer. Chlorogenic acids are relevant coffee quality markers, taste, and aroma precursors as well as important bioactive compounds.

4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.

It has been granted to have property to inhibit protein isoprenyl transferases.

2,3-dihydroxy-3-methylbutanoic acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins, thereby increasing muscle mass and improving recovery from exercise.

3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.

(S)-3-AMino-2-Methylpropanoic acid-HCl is an amino acid derivative that can be an agonist of the excitatory neurotransmitter glutamate and affect the nervous system.

methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect