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  • Apoptosis
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  • Histone Demethylase
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gskj4

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  • Inhibitors & Agonists
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GSK-J4
T31001373423-53-0In house
GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3 me2 demethylases JMJD3 KDM6B and UTX KDM6A (IC50=8.6 6.6 μM). GSK-J4 induces endoplasmic reticulum stress-related apoptosis.
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GSK-J4 Hydrochloride
GSK J4 HCl,GSK J4 HCl (1373423-53-0 free base)
T43831797983-09-5
GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.
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