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Inhibitors & Agonists

h1373

" in TargetMol Product Catalog

Inhibitors & Agonists
1

Adagrasib

T83692326521-71-3

Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.

Kras

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