hbe

HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.

HBED-CC-tris(tert-butyl ester) is a monovalent variant of HBED-CC that can be used in the synthesis of synthetic radiocompounds based on asymmetric HBED-CC that can be used for tumor imaging.

M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of  0.53  μM and 1.39 μM. Anti-tumor activity. M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09  μ

Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: 62.4 nM), JAK (IC50: 1.38 nM). Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF).