ht11 hydrochloride

CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist with IC50 values of 0.03 μM for hCCR1, 0.58 μM for mCCR1, and 0.32 μM for rCCR1. This compound is useful for studying rheumatoid arthritis and other related inflammatory diseases.

cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound comprising an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker, mainly used in the development of SNIPERs for targeted protein degradation[1].

CDK8-IN-11 hydrochloride is a selective and potent inhibitor of CDK8 (IC50: 46 nM) that inhibits the WNT β-catenin signaling pathway and can be utilized for studying colon cancer.

PSB 11 hydrochloride is a human adenosine A3 receptor antagonist.

[DPro10] Dynorphin A (1-11), porcine hydrochloride, is an N-alkylated derivative and potent κ-opioid receptor agonist with a K i value of 0.13 nM, possessing analgesic properties [1] [2].

DC-BPi-11 hydrochloride is a BPTF (bromodomain PHD finger transcription factor) inhibitor with an IC50 value of 698 nM, demonstrating significant anti-proliferative effects on leukemia cells [1].

γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM). γ-Secretase modulator 11 hydrochloride significantly reduces brain Aβ42 levels and rescues the cognitive deficits exhibited by AD model mice. γ-Secretase modulator 11 hydrochloride has shown research potential in Alzheimer's disease.

Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.

[DPro10] Dynorphin A (1-11), porcine, an N-Alkylated derivative, serves as a potent κ-opioid receptor agonist with a Ki value of 0.13 nM, exhibiting analgesic properties [1] [2].

cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.