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Results for "

j 115814j-115814,

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    86
    TargetMol | Activity
  • Peptide Products
    1
    TargetMol | inventory
  • Natural Products
    51
    TargetMol | natural
  • Recombinant Protein
    6
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    1
    TargetMol | Activity
J-115814
J 115814J-115814, (+ -)-,UNII-81DP93CF8M
T32246329716-61-2
J-115814 is a potent feeding stimulant.
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J-147
J147
T19931146963-51-0
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.
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TargetMol | Citations Cited
J-104871
J104871,J 104871,UNII-6137X5QNJF
T24188191088-19-4In house
J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
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10-14 weeks
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ZX-J-19J
N-(2,3-Diphenyl-6-quinoxalinyl)octanamide
T99361352576-02-3In house
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil.
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TargetMol | Inhibitor Sale
Ginkgolide J
BN 52024,7-beta-Hydroxyginkgolide A
T6S2115107438-79-9
Ginkgolide J (BN 52024) has neuroprotective activity, it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.
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Gomisin J
T390466280-25-9
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+ calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells.
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Picrasidine J
T126552
Picrasidine J is a useful organic compound for research related to life sciences and the catalog number is T126552.
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Gnetin J
T125758
Gnetin J is a useful organic compound for research related to life sciences and the catalog number is T125758.
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J 2644
AI3-70691,J2644,J-2644,BRN 1999543
T3224371712-03-3
J 2644 is a bioactive chemical.
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Taxinine J
TN511518457-46-0
Taxinine J possesses inhibitory activity on heptoma cell in vitro.
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Dodoviscin J
TN38851372527-42-8
Dodoviscin J can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells.
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7-Deacetoxytaxinine J
TN322218457-45-9
7-Deacetoxytaxinine J is a natural product for research related to life sciences. The catalog number is TN3222 and the CAS number is 18457-45-9.
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Dysolenticin J
TN39041337973-08-6
Dysolenticin J shows significant vasodilative effects on intact rat aortic rings with a diastolic degree of 87.4% at 10 ug/mL.
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2,7-Dideacetoxytaxinine J
TN2742115810-14-5
2,7-Dideacetoxytaxinine J is a natural product for research related to life sciences. The catalog number is TN2742 and the CAS number is 115810-14-5.
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Derrisisoflavone J
TN54692172624-67-6
Derrisisoflavone J is a natural product for research related to life sciences. The catalog number is TN5469 and the CAS number is 2172624-67-6.
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2-Deacetoxytaxinine J
TN2752119347-14-7
2-Deacetoxytaxinine J shows significant in vitro activity against breast cancer cell line at a concentration of 20 microM and 10 microM in MCF-7 and MDA-MB-231 respectively.
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Decinnamoyltaxinine J
TN378784652-33-5
Decinnamoyltaxinine J is a natural product from Taxus brevifolia Nutt.
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Sofosbuvir impurity J
T129651334513-10-8
Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
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Celosin J
TN14791623405-29-7
Celosin H, celosin I, celosin J could be used as chemical markers for the quality control of C. argentea seeds.
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Cyclocarioside J
T1256491644624-86-1
Cyclocarioside J is a useful organic compound for research related to life sciences. The catalog number is T125649 and the CAS number is 1644624-86-1.
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Glycoside St-J
T82287203513-88-6
Glycoside St-J (Compound 2), a triterpenoid saponin isolated from Anemone flaccida, exhibits antitumor activity by inhibiting HeLa cell proliferation and shows potential for use in the development of novel anticancer agents [1].
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J 2931
J2931,NSC 321569,J-2931
T2418686071-23-0
J 2931 is an inhibitor of mosquito larvae growth.
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6-8 weeks
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Mahuannin J
TN7396
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trans-J-113863
T84888202796-42-7
Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].
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8-10 weeks
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(±)-J 113397
T21999217461-40-0
(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397 inhibited nociceptin orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin orphanin FQ [1].
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10-14 weeks
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J-113863
T11699353791-85-2
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively.
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Nikkomycin pseudo-J
T33672120796-22-7
Nikkomycin pseudo-J is a nikkomycin isolated from Streptomyces tendae.
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Bruceine J
T75558948038-38-8
Bruceine J, a quassinoid naturally derived from the fruits of Br. javanica, exhibits anti-Babesial activity [1].
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Senkyunolide J
T8117894530-86-6
Senkyunolide J, a phthalide isolated from the rhizome of Ligusticum Chuanxiong [1], exhibits medicinal properties.
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Gleditsioside J
T125199253123-52-3
Gleditsioside J is a useful organic compound for research related to life sciences. The catalog number is T125199 and the CAS number is 253123-52-3.
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Macrocarpal J
TN4480179603-47-5
Macrocarpal J has anti-bacterial activity, it also has anti-glucosyltransferase activity.
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Longipedlactone J
TN44481011762-93-8
Longipedlactone J is a natural product of Kadsura, Schisandraceae. The catalog number is TN4448 and the CAS number is 1011762-93-8. Longipedlactone J can be used as a reference standard.
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cis-J-113863
T84887202796-41-6
Cis-J-113863 is a competitive antagonist for the chemokine receptor 1 (CCR1), demonstrating inhibitory concentration 50 (IC50) values of 0.9 nM for human CCR1 receptors and 5.8 nM for mouse CCR1 receptors, respectively [1].
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8-10 weeks
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Verrucarin J
Muconomycin B
T692254643-58-7
Verrucarin J (Muconomycin B), derived from the Myrothecium fungus family, effectively generates reactive oxygen species (ROS) to induce apoptosis in various cancer cell lines, including A549, HCT 116, and SW-620. Besides its anticancer properties, it exhibits antifungal activity against Candida albicans and Mucor miehei. Furthermore, it notably inhibits the arenavirus Junin (JUNV) yield with an IC 50 of 1.2 ng/mL.
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6-8 weeks
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Monacolin J
Antibiotic MB 530A,Lovastatin diol lactone
T1209279952-42-4
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
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TargetMol | Inhibitor Sale
Cynanoside J
TN76621800029-53-1
Cynanoside J, a C21 steroidal glycoside derived from Cynanchum taihangense, exhibits IC50 values of 6.38, 5.82, and 6.76 μM against HL-60, THP1, and Caco2 cell lines, respectively. This compound can be utilized in cancer research [1].
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Inquiry
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J-104129 fumarate
T69576257603-40-0
J-104129 fumarate is a potent M3 muscarinic receptor antagonist.
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6-8 weeks
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Forskolin J
TN407481873-08-7
Forskolin J is a natural product for research related to life sciences. The catalog number is TN4074 and the CAS number is 81873-08-7.
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Diosbulbin J
TN38731187951-06-9
Diosbulbin J is a natural product for research related to life sciences. The catalog number is TN3873 and the CAS number is 1187951-06-9.
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Tenuifoliose J
TN2426147742-14-1
Tenuifoliose J is a natural product from Polygala tenuifolia Willd
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Gancaonin J
TN5635129280-37-1
Gancaonin J is a natural product for research related to life sciences. The catalog number is TN5635 and the CAS number is 129280-37-1.
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Mudanpioside J
TN5856262350-52-7
Mudanpioside J is a natural product for research related to life sciences. The catalog number is TN5856 and the CAS number is 262350-52-7.
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J-31
T69246443325-44-8
J-31 is an inactive conformation inhibitor of ITK.
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6-8 weeks
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J-30
UNII-0896Z9T2XN
T32248916484-16-7
J-30 is a bioactive chemical.
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J-1924
UNII-J744A5NTOH,J 1924
T32247501079-20-5
J-1924 is a bioactive chemical.
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J-1048
T787902374772-60-6
J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/Smad signaling pathway [1].
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6-8 weeks
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Kadsuphilin J
T819951017242-94-2
Kadsuphilin J, a lignan isolated from Kadsura longipedunculata roots, exhibits significant cytotoxicity against several human tumor cell lines, demonstrating its potential as an anticancer agent.
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J-2156
T11700848647-56-3
The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC5
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6-8 weeks
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