loureirin a

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Lourei

Loureirin D is a chalcone from the herbs of Dracaena cochinchinensis.

Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.

Loureirin D (4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone) is isolated from the stem wood of Dracaena loureiri.

Loureirin C can inhibit the activities of thrombin in vitro effectively.

There is a synergistic interaction between loureirin A and Cochinchinenin C, and the fluorescence quenching of HSA by loureirin A (or Cochinchinenin C) is a combined quenching procedure (dynamic and static quenching).