mal-peg-4-lys(tfa)-nh-m-peg24

Mal-PEG4-Lys(TFA)-NH-m-PEG24 is a polyethylene glycol (PEG) derivative designed as a PROTAC linker for synthesizing proteolysis targeting chimeras (PROTACs) [1].

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Mal-PEG4-C2-NH2 TFA, a PEG-based linker, facilitates the assembly of PROTAC molecules by connecting two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].

Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) linker compound, designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].

m-PEG3-Mal is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker with a cleavable bond, frequently used in the production of antibody-drug conjugates (ADCs)[1].

m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

Mal-NH-PEG6-CH2CH2COOPFP ester, a polyethylene glycol (PEG)-based linker, is specifically designed for the synthesis of PROTACs and is known as a PROTAC linker[1].

Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis [1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

m-PEG12-NH-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands necessary for the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system [within cells].

Mal-PEG4-Glu(OH)-NH-m-PEG24 is a polyethylene glycol-based (PEG-based) linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

m-PEG16-Mal is a PEG-based linker for PROTACs that connects two essential ligands necessary for the formation of PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

PROTAC AR Degrader-4, an Androgen Receptor (AR) degrader, incorporates an IAP ligand binding group, a linker, and an AR binding group. It represents a class of degradation inducers known as specific and non-genetic IAP-dependent protein erasers (SNIPERs) [1], operating through a mechanism involving cIAP1.

m-PEG36-Mal is a PEG-based linker for PROTACs, joining two essential ligands necessary for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Aminooxy-PEG-OH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].

Thiol-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derivative frequently used in the construction of PROTACs, bifunctional compounds designed for targeted protein degradation [1].

m-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG)-based linker compound tailored for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG-mal (MW 3400) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system in cells.

m-PEG6-amino-Mal is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-Lys-NHS ester (MW 20,000) is an alkyl ether-based PROTAC linker commonly used in PROTAC synthesis[1].

Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

m-PEG-acrylate (MW 2000) is a polyethylene glycol (PEG) derivative linker that plays a crucial role in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

m-PEG24-Mal is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Mal-NH-PEG4-CH2CH2COOPFP ester, a polyethylene glycol (PEG) based linker, is used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

m-PEG8-Mal is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-triethoxysilane (MW 1000) is a triethoxysilane-functionalized polyethylene glycol (PEG) derivative that serves as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs), which are compounds used for targeted protein degradation[1].

Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

m-PEG-NH2 (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azide-PEG-azide (MW 20000) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker used for the synthesis of PROTACs[1].

m-PEG48-Mal is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a polyethylene glycol (PEG)-based PROTAC linker, ideal for PROTAC synthesis[1].

M-PEG12-Mal is a PEG derivative containing a maleimide group. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group could form a covalent bond with a thiol group , enabling the further connection of biomolecule with a thiol

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a polyethylene glycol (PEG)-based linker crucial for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

ZXH-4-130 TFA is a hetero-PROTAC (CRBN-VHL compound) that efficaciously and selectively mediates the degradation of CRBN, achieving approximately 80% degradation at a concentration of 10 nM in MM1.S cells [1].

m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-triethoxysilane (MW 5000) is a polyethylene glycol-based PROTAC linker suitable for synthesizing PROTACs[1].