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Results for "
nbi 27914 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists3
NBI-27914 hydrochloride
T230571215766-76-9
corticotropin-releasing factor1 (CRF1) receptor antagonist
- $540
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NBI 35965 hydrochloride
T869781782228-59-4
NBI 35965 hydrochloride is a selective CRF1 (corticotropin-releasing factor receptor 1) antagonist that is both orally active and capable of penetrating the brain. It possesses a K i value of 4 nM and a pK i of 8.5, and does not affect CRF2. This compound effectively diminishes CRF or stress-triggered ACTH (adrenocorticotropic hormone) production in vivo, demonstrating pIC 50 values of 7.1 and 6.9. Additionally, NBI 35965 hydrochloride exhibits anxiolytic properties [1] [2].
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