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nov-120101 hydrochloride

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Poziotinib hydrochloride
HM 781-36B hydrochloride,NOV120101 hydrochloride
T87581429757-68-5
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
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Poziotinib
HM781-36B,NOV120101
T26301092364-38-9
Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).
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