Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.

Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase. In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenic E. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections.

Enrofloxacin hydrochloride is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) serves as a potent antibiotic, exhibiting a minimum inhibitory concentration (MIC 90) of 0.312 μg/mL against Mycoplasma bovis and demonstrating inhibitory activity towards the vaccinia virus (VV).