sulfamide

Sulfamide (Sulfuric diamide) is used in organic chemistry for synthesis.

Elaidyl-sulfamide is a sulfamoyl analogue of oleoylethanolamide (OEA). ES is a lipid mediator of satiety that acts through the PPARα.

Azosulfamide is an azo compound with similar antibacterial effect as sulfanilamide.

Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an inhibition constant (Ki) of 79.60 μM [1].

Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.

Firzacorvir is a cyclic sulfamide compound that acts as an HBV core protein modulator and exhibits potent anti-HBV activity, with an EC50 value of < 1 μΜ.

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a sulfamide-containing polypeptide that can be utilized in the synthesis of peptide-agent coupling compounds [1].

Sultopride is a compound that an amino on the sulfamide group of sulpiride is replaced by an ethyl group.

DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.