thalidomide 5,6 cl

Thalidomide-5,6-Cl, a derivative of Thalidomide, serves as a cereblon ligand for the recruitment of CRBN protein. It can be linked to a ligand for protein using a linker to form PROTACs.

Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1.

Thalidomide-5-OH (2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.

Thalidomide-5-methyl is a Thalidomide-based cereblon (CRBN) ligand used for the recruitment of CRBN protein.

Thalidomide-5-NH2-CH2-COOH (compound 114) is a selective inhibitor of the protomyosin receptor kinase and a ligand for E3 ligase, offering potential for studying various diseases.

Thalidomide-5-PEG2-Cl, a Thalidomide-derived cereblon ligand, serves as the ligand for the recruitment of CRBN protein. It can be conjugated to the protein ligand via a linker to produce PROTACs.

Thalidomide-5-COOH is a useful organic compound for research related to life sciences. The catalog number is T64600 and the CAS number is 1216805-11-6.

Thalidomide-5-O-C6-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to another ligand to form proteolysis-targeting chimeras (PROTACs) [1].

Thalidomide-5-O-C5-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to form PROTACs [1].

Thalidomide-5-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment. This compound can be tethered to a protein-targeting ligand using a linker, enabling the formation of PROTACs [1].

Thalidomide-5-PEG7-NH2 hydrochloride is a Thalidomide-based cereblon ligand used for CRBN protein recruitment, and it can be conjugated to a protein ligand with a linker to create PROTACs [1].

Thalidomide-5-O-C3-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].

Thalidomide 5'-amine-alkylC6-amine serves as a specialized cereblon ligand for PROTAC research and development, combining an E3 ligase ligand and an alkylC6 linker with a terminal amine for target protein ligand conjugation. It is among a series of functionalized tool molecules designed for PROTAC R&D.

Thalidomide-5-PEG6-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, facilitates the recruitment of the CRBN protein and can be tethered to a ligand for protein conjugation via a linker to construct PROTACs [1].

Thalidomide-5-O-C12-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a ligand for protein, forms PROTACs [1].

Thalidomide-5-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1].

Thalidomide-Piperazine 5-fluoride is a compound synthesized as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand derived from Thalidomide and utilizing a linker commonly employed in PROTAC technology.

Thalidomide-5-PEG2-NH2 hydrochloride, a Thalidomide-based cereblon ligand, is used for recruiting CRBN protein. It can be linked to a protein ligand via a linker to form PROTACs [1].

Thalidomide-5-propargyne-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, is utilized in recruiting CRBN protein and can be linked to a protein ligand via a linker to form PROTACs [for protein degradation].

Potent and selective cereblon degrader (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable. Steinebach et al (2019) PROTAC-mediated crosstalk between E3 ligases. Chem.Commun.(Camb) 55 1821 PMID:30672516

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide-based cereblon ligand designed for CRBN protein recruitment. It facilitates the formation of PROTAC molecules by linking to target protein ligands, such as THAL-SNS-032, via a connector.

Thalidomide-5,6-F is a cereblon ligand derived from Thalidomide that is utilized for the recruitment of CRBN protein. It can be conjugated to a protein ligand through a linker, thus enabling the formation of PROTACs, a class of molecules with targeted protein degradation capabilities.

Thalidomide-5-CH2-NH2 (hydrochloride) is a Thalidomide derivative that acts as a cereblon ligand for CRBN protein recruitment. This compound can be linked to a protein ligand via a linker to form PROTACs.

Thalidomide-5-piperazine-C-piperidine-CO-C8-NH2 is a coupled compound acting as an E3 ubiquitin ligase ligand-linker conjugate.

Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.

Thalidomide-5-O-C14-NH2 hydrochloride, a cereblon ligand based on Thalidomide, facilitates the recruitment of CRBN protein. By incorporating a linker, this compound can be conjugated to a ligand to create PROTACs [1].

Thalidomide-5-O-C4-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It can be tethered to a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].

Thalidomide-5-O-C2-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to form PROTACs [1].

Thalidomide-Piperazine 5-fluoride hydrochloride, a derivative of the cereblon (CRBN) inhibitor Thalidomide, serves as a ligand for E3 ubiquitin ligase (Ligands for E3 Ligase), facilitating the synthesis of PROTACs [1].

Thalidomide-5-piperazine is a PROTAC target protein ligand.

Thalidomide-5-NH-PEG2-NH2 hydrochloride is a cereblon ligand based on Thalidomide, designed to recruit CRBN proteins. It has the capability to be linked with target protein ligands via a linker, facilitating the formation of PROTAC molecules, such as THAL-SNS-032.

Thalidomide-5-O-C13-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It is designed to conjugate with a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].

Thalidomide-5-O-C8-NH2 hydrochloride is a Thalidomide-based cereblon ligand that recruits CRBN protein and, when connected to a ligand via a linker, forms PROTACs [1].

Thalidomide-5-O-C9-NH2 hydrochloride, a thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be tethered to a protein ligand via a linker, enabling the formation of PROTACs [1].

Thalidomide-5-O-C11-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].

Thalidomide-5-NH-PEG3-NH2 hydrochloride is a cereblon ligand based on Thalidomide that targets CRBN proteins. It utilizes a linker to attach to a target protein ligand, facilitating the formation of a PROTAC molecule, such as THAL-SNS-032.