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Results for "
vimirogant
" in TargetMol Product Catalog- Inhibitors & Agonists2
Vimirogant
VTP-43742
T167871802706-04-2
Vimirogant is a RORγ inhibitor (Ki: <100 nM).
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Vimirogant hydrochloride
T64300
Vimirogant (VTP-43742) hydrochloride is an orally active, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM) that is more than 1000 times more selective than RORα and RORβ. It inhibits Th17 differentiation and IL-17A secretion in mouse spleen cells with an IC50 of 57 nM and does not affect Th1, Th2, or Treg cell differentiation.
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