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Neuroscience ACK

ACK

In molecular biology, acetate kinase , which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria.
Cat No. product name
T2382 VemurafenibHOT Vemurafenib (PLX4032) is a novel and potent B-Raf (V600E) inhibitor (IC50: 31 nM).
T2641 KRCA-0008 KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
T5092 AIM-100 AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
Vemurafenib HOT
T2382CAS 918504-65-1
Vemurafenib (PLX4032) is a novel and potent B-Raf (V600E) inhibitor (IC50: 31 nM).
KRCA-0008
T2641CAS 1472795-20-2
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
AIM-100
T5092CAS 873305-35-2
AIM-100 is a Ack1 inhibitor (IC50: 24 nM).