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ACK

In molecular biology, acetate kinase , which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria.

  • Vemurafenib
    T2382918504-65-1
    Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.
    • $50
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    TargetMol | Citations Cited
  • GNF-7
    T3196839706-07-9
    GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
    • $37
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  • AIM-100
    T5092873305-35-2
    AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
    • $42
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    TargetMol | Inhibitor Sale
  • AZ7550
    T135641421373-99-0
    AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
    • $133
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  • KRCA-0008
    T26411472795-20-2
    KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
    • $39
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    TargetMol | Inhibitor Sale