T5402 |
DDR1-IN-2
|
1429617-90-2
|
100%
|
|
DDR1-IN-2 (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).
|
T10985 |
DDR Inhibitor
|
1644069-80-6
|
97.75%
|
|
DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.
|
T17258 |
WRG-28
|
1913291-02-7
|
97.84%
|
|
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)
|
T7862 |
VU6015929
|
2442597-56-8
|
98.07%
|
|
VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2)( IC50s of 4.67 nM and 7.39 nM, respectively).
|
T9659 |
LCB 03-0110
|
1228102-01-9
|
98.83%
|
|
LCB 03-0110 is a potent inhibitor of discoidin domain receptor family tyrosine kinases and strongly inhibits several tyrosine kinases, including the c-Src family...
|
T11279 |
FGFR1/DDR2 inhibitor 1
|
2308497-58-5
|
99.14%
|
|
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108....
|
T3455 |
Merestinib
|
1206799-15-6
|
99.56%
|
|
LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. LY2801653 selectively b...
|
T4349 |
Sitravatinib
|
1123837-84-2
|
99.74%
|
|
Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
|
T3337 |
Ddr1-In-1
|
1449685-96-4
|
99.84%
|
|
DDR1-IN-1 is an effective and specific DDR1 receptor tyrosine kinase inhibitor (IC50: 105 nM), about 3-fold selectivity over DDR2.
|
T10984 |
DDR-TRK-1
|
1934246-19-1
|
99.86%
|
|
DDR-TRK-1 is a selective discoid domain receptor 1 (DDR1) inhibitor with IC50 value of 9.4 nM. DDR-TRK-1 also inhibits the TRK family.
|
T60186 |
(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide
|
1934246-20-4
|
99.87%
|
|
|