Glucosidase

Glucosidase belongs to the glycoside hydrolase family of enzymes and plays a crucial role in breaking down glucosidic bonds to release glucose. Glucosidase is essential for sugar metabolism in organisms, found across a wide range of sources and present in almost all cellular structures that utilize carbohydrates for energy. This enzyme comes in two main types: β-glucosidase, involved in cellulose metabolism and various physiological pathways, and α-glucosidase, which directly participates in starch and glycogen metabolism. Dysfunctions in these enzymes can lead to metabolic disorders. Moreover, glucosidase serves as a target for various drugs and inhibitors aimed at regulating sugar metabolism in the human body.

Cat. No.	Product name	CAS No.	Purity
T79964	6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone	1622982-59-5	98%
T79964	Compound 1, 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone, is an anthraquinone α-glucosidase inhibitor with an IC50 of 185 μM, and it can be isolated from...
T79980	Flaccidoside III	140400-67-5	98%
T79980	Flaccidoside III, a flavonoid and triterpenoid compound extracted from the aerial parts of N. sativa (Ranunculaceae), demonstrates inhibition of α-Glucosidase (I...
T80017	Casuarictin	79786-00-8	98%
T80017	Casuarictin, a potent competitive inhibitor of α-glucosidase, exhibits an IC50 of 0.21 μg/mL and functions as a presenilin stabilization factor-like (PSFL) prote...
T80708	α-Glucosidase-IN-42		98%
T80708	α-Glucosidase-IN-42 (Compound 26), a 9-O-berberrubine carboxylate derivative, exhibits potent α-glucosidase inhibitory activity with an IC50 value of 1.61 μM and...
T80709	α-Glucosidase-IN-41		98%
T80709	α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its cataly...
T80710	α-Glucosidase-IN-40		98%
T80710	α-Glucosidase-IN-40 (compound 5) serves as a noncompetitive inhibitor of the α-glucosidase enzyme, exhibiting an inhibitory concentration (IC50) of 24.62 μM [1]....
T80711	α-Glucosidase-IN-39		98%
T80711	α-Glucosidase-IN-39 is a potent α-glucosidase enzyme inhibitor, exhibiting an IC50 value of 869.06 ppm. It is applicable for use in antidiabetic studies [1].
T80712	α-Glucosidase-IN-38		98%
T80712	α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor, demonstrating an IC50 of 12.44±0.38 μM, and is significant in the context of Diabetes mel...
T82330	GCase modulator-1	796079-91-9	98%
T82330	GCase Modulator-1 (Compound 9g), a quinazoline derivative, functions as a glucosidase modulator with an AC50 value of 2.23 µM [1].
TN4621	N1,N10-Bis(p-coumaroyl)spermidine	114916-05-1	98%
TN4621	N1,N10-Bis(p-coumaroyl)spermidine is inhibitory to alpha-glucosidase and can be extracted from the herb of alfalfa.
TN4003	Erythro-Guaiacylglycerol beta-coniferyl ether	890317-92-7	98%
TN4003	Erythro-Guaiacylglycerol beta-coniferyl ether is a compound that can be extracted from the stems and leaves of mung beans and has inhibitory effects on alpha-glu...
TN4368	Kaempferol-3,7-di-O-β-glucoside	25615-14-9	99.97%
TN4368	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinestera...
T3235	Rebaudioside A	58543-16-1	99.94%
T3235	Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.
T5489	Tryptophan, N-indol-3-ylacetyl- (6CI)	57105-53-0	99.9%
T5489	Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological ...
TQ0300	Conduritol B epoxide	6090-95-5	99.85%
TQ0300	Conduritol B epoxide is an irreversible inhibitor of β-glucosidase (GCase).
T6723	Voglibose	83480-29-9	99.84%
T6723	Voglibose (Glustat), an N-substituted derivative of valiolamine, exhibits excellent inhibitory activity against α-glucosidases and action against hyperglycemia a...
T3675	1-Deoxynojirimycin	19130-96-2	99.82%
T3675	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.
T8202	Kaempferol 3-O-gentiobioside	22149-35-5	99.78%
T8202	Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a ...
TQ0308	Castanospermine	79831-76-8	99.74%
TQ0308	Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.
TN2326	(Z)-Butylidenephthalide	72917-31-8	99.72%
TN2326	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-...