PKA

protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase . Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

Cat. No.	Product name	CAS No.	Purity
T27525	HA-1004	91742-10-8	99.03%
T27525	HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
T2482	AT13148	1056901-62-2	99%
T2482	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
T4276L	Hydroxyfasudil	105628-72-6	98.79%
T4276L	Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).
T13807	OSIP-486823	200803-37-8	98.59%
T13807	OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.
T6303L	CCT128930 hydrochloride	2453324-32-6	98.55%
T6303L	CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest...
T15798	LX7101	1192189-69-7	98.42%
T15798	LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
T3513	GSK180736A	817194-38-0	98.16%
T3513	GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), b...
T67755	Protein kinase G inhibitor-1	354544-70-0	98.11%
T67755	Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.
T24051	Exisulind	59973-80-7	98.08%
T24051	Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity in solid tumour and haematologic...
TP1523	PKG inhibitor peptide TFA (82801-73-8 free base)	TP1523	98%
TP1523	PKG inhibitor peptide TFA (82801-73-8 free base) is an inhibitor of ATP-competitive cGMP-dependent protein kinase (PKG).
T4661	PKG drug G1	374703-78-3	97.57%
T4661	PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
T39217	PKA-IN-1	179985-52-5	97.52%
T39217	PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to study dise...
T3498	CCG215022	1813527-81-9	97.46%
T3498	CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.
T16791	Rottlerin	82-08-6	97.41%
T16791	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKC...
T22833	H-9 dihydrochloride	116700-36-8	96.57%
T22833	H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.H-...
T21983L	PKI 14-22 amide, myristoylated Acetate	T21983L	96.34%
T21983L	PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.
TN4114	Gardenin A	21187-73-5	95.15%
TN4114	Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
T77570	AP-C2	682793-07-3	100%
T77570	AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
TP1789L	Malantide acetate(86555-35-3 free base)	TP1789L	100%
TP1789L	Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide tha...
T3269	Metadoxine	74536-44-0	100%
T3269	Metadoxine (Metadoxil) is a neurotransmitter stimulant.