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TOPK

T-LAK cell-originated protein kinase (TOPK) is a MAPKK-like kinase which plays a role in cell cycle regulation and mitotic progression. As a consequence, TOPK expression is minimal in differentiated cells, although its overexpression is a pathophysiological feature of many tumours. Hence, TOPK has garnered interest as a cancer-specific biomarker and biochemical target with the potential to enhance cancer therapy whilst causing minimal harm to normal tissues.

Cat No.	product name
T4135	OTS964	OTS964 is a potent and selective TOPK inhibitor with potential anticancer activity.
T4134	OTS514 hydrochloride(1338540-63-8(free base))	OTS514 is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).

OTS964

T4135CAS 1338545-07-5

OTS964 is a potent and selective TOPK inhibitor with potential anticancer activity.

OTS514 hydrochloride(1338540-63-8(free base))

T4134CAS T4134

OTS514 is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).