Cucumegastigmane I is a natural product of Trichosanthes, Cucurbitaceae. The catalog number is TN5332 and the CAS number is 929881-46-9. Cucumegastigmane I can be used as a reference standard.

Bryonolol is a natural product of Trichosanthes, Cucurbitaceae. The catalog number is TN3544 and the CAS number is 39765-50-9. Bryonolol can be used as a reference standard.

Stigmastane-3 beta, 6 alpha-diol and stigmastane-3 beta, 6 beta-diol possess marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, the 50% inhibitory dose is 0.5--1.0 mg/ear.

Karounidiol exhibits cytotoxicity especially against a human renal cancer, it markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse

Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine can alleviate oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1 p38 MAPK pathway.