T13837 |
PROTAC CRABP-II Degrader-2
|
1225383-38-9
|
98%
|
|
PROTAC CRABP-II Degrader-2 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
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T18687 |
SNIPER(ABL)-020
|
T18687
|
98%
|
|
SNIPER(ABL)-020 is a chemical compound consisting of Dasatinib, an ABL inhibitor, and Bestatin, an IAP ligand, conjugated with a linker. This compound effectivel...
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T16905 |
SNIPER(BRD)-1
|
2095244-54-3
|
98%
|
|
SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degr...
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T13836 |
PROTAC CRABP-II Degrader-1
|
1225383-40-3
|
98%
|
|
PROTAC CRABP-II Degrader-1 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
|
T18686 |
SNIPER(ABL)-019
|
T18686
|
98%
|
|
SNIPER(ABL)-019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting a DC50...
|
T13892 |
SNIPER(TACC3)-2
|
T13892
|
98%
|
|
SNIPER(TACC3)-2 targets TACC3 protein degradation via the ubiquitin-proteasome pathway. It induces cancer cell death.
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T18692 |
SNIPER(ABL)-047
|
T18692
|
98%
|
|
SNIPER(ABL)-047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels, achi...
|
T18694 |
SNIPER(ABL)-050
|
T18694
|
98%
|
|
SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker. This conjugation results in the reduct...
|
T17545 |
Biotin-BS
|
T17545
|
98%
|
|
Biotin-BS is a chemical compound composed of two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and biotin. These ligands are interconnected through linkers....
|
T18688 |
SNIPER(ABL)-024
|
2222355-77-1
|
98%
|
|
SNIPER(ABL)-024, a compound that conjugates GNF5 (ABL inhibitor) to an LCL161 derivative (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, a...
|
T18605 |
PROTAC ERα Degrader-2
|
1351169-29-3
|
98%
|
|
PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader. It achie...
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T18690 |
SNIPER(ABL)-039
|
2222354-29-0
|
98%
|
|
SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 1...
|
T18691 |
SNIPER(ABL)-044
|
T18691
|
98%
|
|
SNIPER(ABL)-044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a ...
|
T18697 |
SNIPER(ER)-87
|
2222354-91-6
|
98%
|
|
SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (ER...
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T18684 |
SNIPER(ABL)-013
|
T18684
|
98%
|
|
SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 20...
|
T17706 |
BzNH-BS
|
T17706
|
98%
|
|
BzNH-BS is a chemical compound comprising two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide. The ligands are interconnected through linker...
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T18695 |
SNIPER(ABL)-058
|
2222354-61-0
|
98%
|
|
SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein ...
|
T18635 |
PROTAC RAR Degrader-1
|
1351169-27-1
|
98%
|
|
PROTAC RAR Degrader-1, an RAR degrader, consists of a cIAP1 ligand binding group, a linker, and an RAR ligand binding group. It achieves maximal RAR degradation ...
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T18693 |
SNIPER(ABL)-049
|
T18693
|
98%
|
|
SNIPER(ABL)-049, a compound that conjugates Imatinib (ABL inhibitor) with Bestatin (IAP ligand) through a linker, effectively reduces BCR-ABL protein levels, dem...
|
T18596 |
PROTAC AR Degrader-4
|
1351169-31-7
|
98%
|
|
PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degrad...
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