(±)7(8) epdpa

Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.

5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may exhibit anti-influenza virus activity.

8-Acetyl-7-Hydroxycoumarin is a natural compound,with Antifungal and antibacterial activities

3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis.

7-methoxy-8-hydroxy-4-methylcoumarin is a compound isolated from Citrus aurantium.

1,10:4,5-Diepoxy-7(11)-germacren-8-one is a natural product for research related to life sciences. The catalog number is TN2476 and the CAS number is 32179-18-3.

8-O-Methylretusin-7-O-beta-D-glucopyranoside is a useful organic compound for research related to life sciences and the catalog number is T124388.

Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined. 1.Serhan, C.N., Gotlinger, K., Hong, S., et al.Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienesJ. Immunol.176(3)1848-1859(2006) 2.Ariel, A., and Serhan, C.N.Resolvins and protectins in the termination program of acute inflammationTRENDS in Immunology28(4)176-183(2007) 3.Schwab, J.M., Chiang, N., Arita, M., et al.Resolvin E1 and protectin D1 activate inflammation-resolution programmesNature447(7146)869-874(2007)

1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66423 and the CAS number is 112811-57-1.

2-Amino -7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,3,5-tri-O-actyl-xylofuranosyl)purine is a useful organic compound for research related to life sciences. The catalog number is TNU1331 and the CAS number is 2389988-52-5.

[(2R,3S,4R,5R)-3,4-diacetyloxy-5-[2-amino-7-(cyclopropylmethyl)-8-oxopurin-9-yl]oxolan-2-yl]methyl acetate is a useful organic compound for research related to life sciences and the catalog number is TNU1306.

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a natural product for research related to life sciences. The catalog number is TN3267 and the CAS number is 144398-34-5.

5-Hydroxy-7-methoxy-8-methylflavanone is a useful organic compound for research related to life sciences and the catalog number is T131489.

Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides

Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside

Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist for the vasoactive intestinal peptide 1 (VIP 1) receptor.

7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM.

7-Amino-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T67151.

(6R,7R)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66940 and the CAS number is 30246-33-4.

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate is a useful organic compound for research related to life sciences and the catalog number is T64681.

2-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine (catalog number TNU0169, CAS number 2389988-30-9) is a valuable organic compound for life sciences research.

TLR7/8 agonist 7, a compound that functions as a TLR7/8 agonist, plays a pivotal role in activating various immune cells and is instrumental in the synthesis of immune-stimulating antibody conjugate (ISAC) molecules. This compound holds significant potential for research in immunology.

Nucleoside Derivatives - 7-Deaza-8-aza-purine nucleosides

(±)7(8)-DiHDPA, a major metabolite of docosahexaenoic acid produced via oxidation by cytochrome P450 epoxygenases, inhibits aggregation and thromboxane synthesis in isolated platelets.

2',4'-Dihydroxy-7-methoxy-8-prenylflavan is a natural product used for life sciences research [Catalog No. TN2720, CAS No. 331954-16-6].

7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors. 1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery and SAR of novel 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: Identification of copanlisib (BAY 80-6946)ChemMedChem.11(14)1517-1530(2016)

7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a valuable organic compound for life sciences research [Catalog No. TNU0451, CAS No. 2389988-55-8].

8-Aza-7-bromo-7-deazaguanosine is a nucleoside derivative, specifically a 7-deaza-8-aza-purine nucleoside, which serves as a halo-nucleoside, scaffold, and template.

Selina-4(15),7(11)-dien-8-one is a natural product for research related to life sciences. The catalog number is TN3467 and the CAS number is 54707-47-0.

7-methyl-8-oxononanoic acid is an intermidate for synthesis of conjugated molecules. The acid group can derivatize amine-containing molecules in the presence of activators such as EDC or HATU.

Benzoic acid, m-isopropoxy-, 7-nitro-8-quinolyl ester is a bioactive chemical.

15,16-Epoxy-15-ethoxy-6beta,13-dihydroxylabd-8-en-7-one is a natural product for research related to life sciences. The catalog number is TN2633 and the CAS number is 1374328-47-8.

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine is a useful organic compound for research related to life sciences and the catalog number is TNU0394.

3-(1,1-Dimethylallyl)-8-hydroxy-7-methoxycoumarin is a natural product for research related to life sciences. The catalog number is TN2847 and the CAS number is 61899-42-1.

8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66320 and the CAS number is 853029-57-9.

7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a nucleoside derivative (xylo-nucleoside), N-methylated alkylated nucleoside, and an 8-modified purine nucleoside.

2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a valuable organic compound for life sciences research (catalog number: TNU1351, CAS number: 2389988-75-2).

Daphnetin 7-methyl ether has anti-inflammatory activity.

(±)7(8)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid (DPA), formed via cytochrome P450 (CYP) metabolism, and can be further metabolized to (±)7(8)-DiHDTE by epoxide hydrolase.

7-Methoxy-8-(3-methyl-2-oxobutoxy)-2H-1-benzopyran is a useful organic compound for research related to life sciences. The catalog number is T125498 and the CAS number is 188426-72-4.

2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,5-di-O-acetyl-3-deoxy-3-fluoro-ribofuranosyl)purine is a useful organic compound for research related to life sciences. The catalog number is TNU1353 and the CAS number is 2389986-90-5.

7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] .

6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide is a useful organic compound for research related to life sciences and the catalog number is T124600.

(6R,7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65519 and the CAS number is 113479-65-5.

5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside is a natural product for research related to life sciences. The catalog number is TN5451 and the CAS number is 710952-13-9.

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin is a natural product for research related to life sciences. The catalog number is TN3259 and the CAS number is 131652-35-2.

Nucleoside Derivatives - 8-Modified purine nucleosides; N-Methylated alkylated nucleosides

(6R,7R)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T64947 and the CAS number is 24701-69-7.

7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy guanosine, catalog number TNU1333 and CAS number 2389988-54-7, is a valuable organic compound used in life sciences research.

7-Hydroxy-4-methyl-8-nitrocoumarin, a derivative of coumarin, functions as a modified coumarin compound.