(2 pyridyldithio) peg4 propargyl

(2-Pyridyldithio)-PEG4-propargyl is a polyethylene glycol (PEG)-based linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

1,1,1-Trifluoroethyl-PEG4-propargyl is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker, assisting in the synthesis of PROTACs[1].

Propargyl-PEG4-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Propargyl-PEG4-amine, a PEG-based PROTAC linker, can be used in the synthesis of PROTACs.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker commonly used in the synthesis of antibody-drug conjugates (ADCs)[1].

Aminooxy-amido-PEG4-propargyl is a 4-unit PEG ADC linker, non-cleavable and specifically designed for the synthesis of antibody-drug conjugates (ADCs) [1].

Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

Desthiobiotin-PEG4-propargyl is a PEG-coupled PROteolysis TArgeting Chimeric (PROTAC) linker used in PROTAC synthesis.

Propargyl-PEG4-S-PEG4-acid, a polyethylene glycol (PEG)-based PROTAC linker, is suitable for synthesizing Proteolysis Targeting Chimera (PROTACs) [1].

Mal- PEG4- propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Propargyl-PEG4-S-PEG4-Boc is a polyethylene glycol (PEG) based linker designed for PROTAC synthesis [1].

S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly used in synthesizing proteolysis-targeting chimeras (PROTACs) [1].

N-PEG3-N'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-derived linker used in the fabrication of proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a polyethylene glycol (PEG) based PROTAC linker used for synthesizing PROTACs[1].

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can be used to synthesize ADC inhibitors of Galectin-3[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Propargyl-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].

m-PEG3-S-PEG4-propargyl is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation using the ubiquitin-proteasome system within cells.

Propargyl-PEG4-alcohol is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-beta-D-glucose is a polyethylene glycol (PEG) derivatized PROTAC linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Propargyl-PEG4-Sulfone-PEG4-Boc is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG4-methylamine is a polyethylene glycol (PEG) derived linker essential for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Bis-propargyl-PEG4 is a PEG-based PROTAC linker utilized in PROTAC synthesis and specifically employed in the synthesis of demethylvancomycin dimers[1][2].

Propargyl-PEG4-tetra-Ac-beta-D-glucose, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs [1].

Azido-PEG4-propargyl is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker utilized in the efficient synthesis of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG4-sulfonic acid, a PEG4-based linker compound, is used in PROTAC synthesis[1].

Propargyl-PEG4-hydrazide is a non-cleavable 4-unit polyethylene glycol (PEG) linker tailored for antibody-drug conjugate (ADC) synthesis [1].

Thalidomide-O-amido-PEG4-propargyl is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-derived PROTAC linker used for synthesizing PROTACs [1].

(2-Pyridyldithio)-PEG4 acid is a four-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. It serves as a crucial component in the conjugation of antibodies and drugs, enabling targeted drug delivery and enhanced therapeutic efficacy. This linker possesses a (2-pyridyldithio) group at one end, facilitating the attachment of the linker to the specific site on the antibody molecule. The PEG4 chain provides the necessary flexibility and biocompatibility for optimal drug release while maintaining stability throughout the circulation in the body. Ultimately, (2-Pyridyldithio)-PEG4 acid is instrumental in the development and advancement of ADCs, a promising approach in cancer therapy.