(s) purvalanol b

(S)-Purvalanol B, the S enantiomer of Purvalanol B, is an inhibitor of cyclin-dependent kinase (CDK).

Purvalanol B (NG 95) is a CDK inhibitor that targets Cdk2 cyclin A, Cdk2 cyclin E, Cdk5 p35, and Cdk2 cyclin B, with IC50 values of 6, 9, 6, and 6 nM, respectively.

(S)-β-aminoisobutyric acid is a non-protein amino acid derived from the catabolism of valine and thymine.

(-)-(S)-B-973B is an effective allosteric agonist and positive allosteric modulator of α7 nAChR.

(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is an essential organic compound used in life sciences research. The catalog number is T66164 and the CAS number is 72120-71-9.

Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1].

(S)-9-((tert-Butyldimethylsilyl)oxy)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione is a useful organic compound for research related to life sciences and the catalog number is T64821.

(S)-tert-Butyl 2-(3-amino-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T65674 and the CAS number is 109010-60-8.

[Ala127] Hepatitis B Virus Pre-S Region (120-131) is a peptide with the sequence MQWNSTAFHQT, potentially useful for studies on activity enhancement [1].

(S)-3-((tert-Butoxycarbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid is a valuable organic compound for life sciences research, catalog number T66181 and CAS number 500770-78-5.

(S)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-5H-dibenz[b,f]azepine is a useful organic compound for research related to life sciences. The catalog number is T67268 and the CAS number is 942939-38-0.

VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. VMY-1-103 , but not purvalanol B, significantly decreased the proportion of cells in S phase and increased the proportion of cells in G(2)/M. VMY-1-103 increased the sub G(1) fraction of apoptotic cells, induced PARP and caspase-3 cleavage and increased the levels of the Death Receptors DR4 and DR5, Bax and Bad while decreasing the number of viable cells, all supporting apoptosis as a mechanism of cell death. VMY-1-103 possesses unique antiproliferative capabilities and that this compound may form the basis of a new candidate drug to treat medulloblastoma.

(S)-3-AMino-2-Methylpropanoic acid-HCl is an amino acid derivative that can be an agonist of the excitatory neurotransmitter glutamate and affect the nervous system.

3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 3.5.1.6), the last step in pyrimidine degradation. Beta-ureidopropionase deficiency is an inborn error of pyrimidine degradation associated with neurological abnormalities.