(s) tco peg4 acid

(S)-TCO-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid) is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.

(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate, consisting of a VHL ligand based on (S,R,S)-AHPC combined with a 4-unit PEG linker.

Benzyloxy carbonyl-PEG4-acid is a linker with a benzyl protecting group and a carboxylic acid. The carboxylic acid can undergo reactions with primary amines with the help of activators (EDC or HATU). The benzyl protecting group can be removed via hydrogenolysis.

(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized ligand-linker for E3 ligase-based systems, comprising the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, commonly used in PROTAC technology.

(S,R,S)-AHPC-Me-decanedioic acid is a ligand-linker conjugate for E3 ligases, intended for PROTAC synthesis.

Acid-PEG4-S-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules and enables selective protein degradation through the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-PEG2-acid is a PEG-based linker used in PROTACs, connecting two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

m-PEG4-C6-phosphonic acid ethyl ester, a polyethylene glycol (PEG)-based linker compound, is used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

TCO-PEG4-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

S-acetyl-PEG4-alcohol is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methylamino-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker incorporating biotin for labeling, making it a versatile tool in PROTAC synthesis[1].

Carboxy-PEG4-sulfonic acid is a PEG-based linker frequently used in PROTAC synthesis [1].

SPDP-PEG4-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group, primarily used in PROTAC synthesis [1].

Acid-C2-PEG4-C2-NHS ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Benzyl-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for PROTAC molecule formation, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG4-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

S-acetyl-PEG3-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

BDP FL-PEG4-TCO is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis [1].

Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.

TCO-PEG4-TCO is a PEG-based linker used in PROTACs that connects two ligands critical for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker which may be useful in the development of antibody drug conjugates.

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) [1].

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker used in PROTAC synthesis [1].

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-S-PEG4-Boc is a polyethylene glycol (PEG) based linker designed for PROTAC synthesis [1].

Lipoamido-PEG4-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG36-acid is a PEG-based linker for PROTACs (proteolysis-targeting chimeras) that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Carboxy-PEG4-phosphonic acid, a polyethylene glycol (PEG)-derived linker, is utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-(m-PEG4)-N'-(PEG2-acid)-Cy5 is a polyethylene glycol (PEG)-derived linker compound utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs) [1].

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

Acid-PEG8-S-S-PEG8-acid, a PEG-based linker for PROTACs, joins two essential ligands vital for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

S-Bis-(PEG4-Boc) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Acid-PEG4-mono-methyl ester, a PEG- and Alkyl ether-based PROTAC linker, can be employed for PROTAC synthesis[1].

S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

Propargyl-PEG4-S-PEG4-acid, a polyethylene glycol (PEG)-based PROTAC linker, is suitable for synthesizing Proteolysis Targeting Chimera (PROTACs) [1].

Bromo-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

N-Biotin-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker used for the synthesis of PROTACs [1].

Cl-PEG4-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs, serving as an integral compound [1].