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Results for "

(s,r,s) ahpc c2 nh2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    6590
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(S,R,S)-AHPC-C2-NH2
T397362241643-69-4
(S,R,S)-AHPC-C2-NH2 is a synthesized conjugate that combines the VH032-based VHL ligand with a linker, designed for use in PROTAC technology as an E3 ligase ligand-linker.
  • $1,520
Backorder
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QTY
(S,R,S)-AHPC-C2-NH2 dihydrochloride
T398712341796-73-2
(S,R,S)-AHPC-C2-NH2 dihydrochloride, a combination of a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker, facilitates the synthesis of various PROTACs.
  • $597
35 days
Size
QTY
NH2-C4-NH-Boc
T1848568076-36-8
NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.
  • $29
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NH2-C5-NH-Boc
T1861751644-96-3
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.
  • $33
In Stock
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5-Ethynyl-2'-deoxyuridine
T1734161135-33-9
5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.
  • $33
In Stock
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QTY
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TargetMol | Citations Cited
NH2-C2-NH-Boc
T1861657260-73-8
NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.
  • $41
In Stock
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QTY
TargetMol | Inhibitor Sale
1,2-Bis(2-iodoethoxy)ethane
T1731936839-55-1
1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker used in the synthesis of MT802 and SJF620, which are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively [1].
  • $29
In Stock
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QTY
TargetMol | Inhibitor Sale
(S,R,S)-AHPC
T84121448297-52-6
(S,R,S)-AHPC (VH032-NH2) is a VH032-based ligand for recruiting the von Hippel-Lindau (VHL) protein, potentially useful for the targeted degradation of the androgen receptor.
  • $59
In Stock
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(S,R,S)-AHPC hydrochloride
T42071448189-80-7
(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
  • $48
In Stock
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NH2-C6-NH-Boc
T1848751857-17-1
NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].
  • $29
In Stock
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(S,R,S)-AHPC TFA
T179271631137-51-3
(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to create PROTACs (e.g., GMB-475), which effectively induce the degradation of BCR-ABL1, demonstrated by an IC50 of 1.11 μM in Ba/F3 cells.
  • $30
In Stock
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(S,R,S)-AHPC-C10-NH2
T178812341796-74-3
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising an (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
  • $51
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QTY
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2-Phthalimidehydroxy-acetic acid
T17330134724-87-1
2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker utilized in PROTAC synthesis.
  • $59
In Stock
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TargetMol | Inhibitor Sale
Cbz-NH-PEG12-C2-acid
T177191334177-88-6
Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
  • $53
In Stock
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Pomalidomide-PEG4-C2-NH2
T179162225940-52-1
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.
  • $30
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride
T18669L2471970-07-5
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating a VHL ligand and a linker.
  • $148
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TargetMol | Inhibitor Sale
Thalidomide-NH-C2-PEG3-OH
T93822140807-23-2
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.
  • $148
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Thalidomide-NH-PEG1-NH2 hydrochloride
T94012154342-56-8
Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker[1].
  • $61
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dMCL1-2
T136572351218-88-5In house
dMCL1-2 is a potent and selective myeloid leukemia 1 (MCL1) degrading agent based on PROTAC, binding to MCL1 with a KD of 30 nM and activating the apoptosis mechanism by degrading MCL1.
  • $3,200
3-6 months
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(S)-Thalidomide
T12644L841-67-8In house
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic, and pro-apoptotic activities, used in studying leprosy erythema nodosum and myeloma.
  • $56
In Stock
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Boc-NH-PEG7-NH2
T14756206265-98-7
Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.
  • $29
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TargetMol | Inhibitor Sale
Thalidomide-NH-C6-NH2 hydrochloride
T400032375194-37-7
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
  • $33
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DBCO-S-S-PEG3-biotin
T150761430408-09-5
DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.
  • $60
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG4-NH2
T15190L2010159-57-4
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate, consisting of a VHL ligand based on (S,R,S)-AHPC combined with a 4-unit PEG linker.
  • $39
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PROTAC ERRα ligand 2
T58352306388-57-6
PROTAC ERRα ligand 2 is an inverse agonist for the estrogen-related receptor α (ERRα) with an IC50 of 5.67 nM.
  • $60
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG2-N3
T179132010159-45-0
(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate comprising a (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker.
  • $33
In Stock
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TargetMol | Inhibitor Sale
Boc-NH-PEG12-NH2
T176681642551-09-4
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
  • $29
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG2-NH2
T179252010159-60-9
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate, incorporating the (S,R,S)-AHPC based VHL ligand and a 2-unit PEG linker used in PROTAC synthesis.
  • $268
Backorder
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TargetMol | Inhibitor Sale
TSPO ligand-2 
T600151160640-95-8
TSPO ligand-2 (Carbonic acid) is a ligand of AUTAC1 which contains a p-fluorobenzylguanine and a Fumagillol moiety.
  • $58
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TargetMol | Inhibitor Sale
S-acetyl-PEG2-Boc
T186561820641-93-7
S-acetyl-PEG2-Boc (S-Acetyl-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. S-acetyl-PEG2-Boc can be used in the synthesis of PROTACs.
  • $29
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-C10-NH2 dihydrochloride
T186612341796-75-4
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate, incorporating an (S,R,S)-AHPC-based VHL ligand and a linker[1].
  • $385
35 days
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QTY
TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
T179222097971-11-2
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.
  • $39
In Stock
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TargetMol | Inhibitor Sale
Pomalidomide-C2-NH2 hydrochloride
T77612305369-00-8
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and a linker used in [PROTAC] technology.
  • $31
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC
T400282055344-67-5
(S,R,S)-AHPC is a VHL ligand that used in the recruitment of the VHL protein.
  • $59
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-Me hydrochloride
T136711948273-03-7
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is utilized in the synthesis of ARV-771, a potent BET protein degrader. It selectively degrades BET protein in castration-resistant cells with a DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, it serves as the VHL ligand from (S,R,S)-AHPC for recruiting von Hippel-Lindau (VHL) protein.
  • $35
In Stock
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TargetMol | Inhibitor Sale
Boc-NH-C12-NH2
T17652109792-60-1
Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.
  • $29
In Stock
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TargetMol | Inhibitor Sale
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
T188192376990-30-4
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride, incorporating an E3 ligase ligand and a linker, can be used as an immunomodulator for the treatment of cancer.
  • $30
In Stock
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TargetMol | Inhibitor Sale
Pomalidomide-PEG3-C2-NH2
T178832093416-31-8
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.
  • $195
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Hydroxy-PEG4-(CH2)2-Boc
T15529518044-32-1
Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.
  • $29
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-C4-NH2 hydrochloride
T186402245697-83-8
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) is a synthesized E3 ligase ligand-linker conjugate comprising the (S,R,S)-AHPC-based VHL ligand and a linker.
  • $53
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
T179242097973-72-1
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC based VHL ligand and a 2-unit PEG linker used in the synthesis of PROTAC.
  • $34
In Stock
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TargetMol | Inhibitor Sale
Thalidomide-O-amido-PEG3-C2-NH2 TFA
T77581957236-21-3
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.
  • $33
In Stock
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TargetMol | Inhibitor Sale
Thalidomide-O-amido-PEG2-C2-NH2 TFA
T179181957235-75-4
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a 2-unit PEG linker, utilized in PROTAC technology.
  • $33
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride
T186752341796-76-5
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker[1].
  • $34
In Stock
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TargetMol | Inhibitor Sale
Pomalidomide-C2-NH2
T178751957235-66-3
Pomalidomide-C2-NH2 (4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthesized E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
  • $30
In Stock
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TargetMol | Inhibitor Sale
Boc-NH-PEG11-NH2
T176651233234-77-9
Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.
  • $89
In Stock
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TargetMol | Inhibitor Sale
(S,R,S)-AHPC-Me
T77521948273-02-6
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is an (S,R,S)-AHPC-based VHL ligand used to recruit the von Hippel-Lindau (VHL) protein. It is utilized in the synthesis of ARV-771, a VHL E3 ligase-based BET PROTAC degrader that effectively degrades BET proteins in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
  • $39
In Stock
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(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride
T362702376990-28-0
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
  • $78
5 days
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PROTAC BRD4 ligand-2 hydrochloride
T77921
PROTAC BRD4 Ligand-2 Hydrochloride serves as a ligand targeting the BRD4 protein, specifically designed for use with PROTAC CFT-2718.
  • Inquiry Price
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Thalidomide-5-NH-PEG3-NH2 hydrochloride
T848092863635-01-0
Thalidomide-5-NH-PEG3-NH2 hydrochloride is a cereblon ligand based on Thalidomide that targets CRBN proteins. It utilizes a linker to attach to a target protein ligand, facilitating the formation of a PROTAC molecule, such as THAL-SNS-032.
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