[pthr-3]-cdk5 substrate (tfa)

[pThr3]-CDK5 Substrate TFA is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM.

[pThr3]-CDK5 Substrate TFA, a potent Phospho-Thr3CDK5 Substrate, originates from the histone H1 peptide sequence that binds to CDK5's active site. This substrate undergoes phosphorylation by CDK5, demonstrating a K_m value of 6 µM [1].

3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) is a synthetic peptide of 23 amino acid residue. The Asp-Tyr-Lys-Xaa-Xaa-Asp motif is repeated three times in the peptide.

N-Formyl-Met-Ala-Ser TFA is a peptide, binds to formyl peptide receptors on neutrophils.N-Formyl-Met-Ala-Ser Peptide (fMet-Ala-Ser) binds to formyl peptide receptors on neutrophils. N-Formylmethionine-containing peptides including the most potent and know

Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.

Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression

Autocamtide 2 TFA is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). Autocamtide 2 TFA can be used in the CaMKII activity assay.

JAG-1, scrambled TFA is a scrambled sequence of JAG-1(188-204).

Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 Substrate acetate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.

Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ～1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a 16-1 expression.

Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats.

DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.

Histatin 3, a salivary antimicrobial peptide, exhibits activity against C. albicans with an LC50 of 9.2 µM. Additionally, at a concentration of 12 µM, it promotes actin polymerization in cell-free assays.

Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmol/kg to an ob/ob mouse diabetes model, GIP-1 (3-42) elevates plasma glucose levels and lowers plasma insulin levels, demonstrating its effect on reducing insulin secretion from BRIN-BD11 pancreatic cells at a concentration of 100 nM.

ACTH (1-14) (TFA) is a polypeptide of corticotrophin, which promotes the release of cortisol.

MART-1 (26-35) (human) TFA is an amino acid residue of 26-35 protein.

TAT-DEF-Elk-1 TFA is a cell-penetrating peptide Elk-1 inhibitor, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 act

C3a (70-77) TFA (Complement 3a (70-77) TFA) is a COOH-terminal fragment of the C3a anaphylatoxin peptide.

Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 μM.

(S)-2-((tert-Butoxycarbonyl)amino)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65844 and the CAS number is 200124-22-7.

Foxy-5 TFA, a WNT5A agonist and mimicking peptide of WNT5A (a non-canonical Wnt family member), induces cytosolic free calcium signaling without altering β-catenin activation. This compound inhibits the migration and invasion of epithelial cancer cells and significantly diminishes the metastatic progression of WNT5A-low prostate cancer cells in an orthotopic mouse model [1] [2] [3] [4].

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide.

NFF-3 TFA, a selective matrix metalloproteinase (MMP) substrate, specifically interacts with MMP-3 and MMP-10 for hydrolysis. Additionally, it undergoes cleavage by trypsin, hepatocyte growth factor activator, and factor Xa. When labeled with the CyDye pair, Cy3/Cy5Q, NFF-3 TFA generates fluorescence in cell assays, facilitating the detection of cell activity [1].

Sakamototide substrate peptide TFA is a peptide substrate of the AMPK kinase family, used to determine kinase activity.

BQ-3020 (TFA) is a selective ETB receptor agonist that inhibits [125I] et-1 binding to the ETB receptor in the cerebellum with a 0.2nm IC50, causing vasoconstriction.

This is a strongly agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5.

Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide.

PGLa TFA is a cationic antimicrobial peptide (AMP) originally isolated from frog. It has been shown to have antibacterial,antifungal,and antiviral,activities.

Calcitonin,eel TFA is a thyroid hormone polypeptide that can regulate calcium homeostasis and is widely used in the study of postmenopausal osteoporosis.

TNF-α (46-65), human (TFA) is a peptide of human TNF-α.

TAT (48-57) (TFA) is a cellular permeability peptide derived from hiv-1 transcriptional activator (TAT) protein residue 48-57.

PGlu-3-methyl-His-Pro-NH2 TFA enhances binding to pituitary TRH receptors, thereby increasing the stimulation of thyroid-stimulating hormone (TSH) release from the pituitary.

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA, is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3) [1].

Phospho-Glycogen Synthase Peptide-2 (substrate) serves as a peptide substrate for glycogen synthase kinase-3 (GSK-3) and is used for the affinity purification of protein-serine kinases [1].

[Ala1,3,11,15]-Endothelin (53-63) (TFA) is a selective ET B agonist with IC50 values from 0.33 nM to 0.61 nM, indicating a high affinity for ET B receptors, and is used in vasoconstriction research.

Calcineurin substrate (TFA) is a polypeptide derived from the regulatory RII subunit of camp-dependent protein kinase.Calcineurin substrate (TFA) can be used to determine the activity of Calcineurin.

Calcineurin substrate (TFA), a peptide derived from the regulatory RII subunit of cAMP-dependent protein kinase, is utilized in the calcineurin activity assay [1].

PKI(5-24) TFA is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) with potent and competitive inhibition properties, exhibiting a K i of 2.3 nM. It corresponds to residues 5-24 of the natural heat-stable protein kinase inhibitor [1][2].

Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial c

Peptide YY (PYY) (3-36), human (TFA) is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite[1].

BLP-3, an endogenous peptide derived from X. laevis skin, exhibits antibacterial efficacy against N. meningitidis, N. gonorrhoeae, N. lactamica, and N. cinerea at a concentration of 20 µg/ml. Characterized by its ability to fold into an alpha-helix, BLP-3 penetrates and disrupts bacteriomimetic membranes, underlying its mechanism of action.

Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to inductio

CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins. It can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin, Ca2+ channels, and pumps.

CRF, bovine (TFA) is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM[1]. CRF shows pEC50s of 11.16, 8.53 and 8

Secretin, porcine TFA (Porcine secretin TFA) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.Secretin porcine stimulates pancreatic and gastric secretions to ai

Gap19 TFA is a peptide derived from nine amino acids of Cx43 cytoplasmic ring (CL), an effective, selective connexin 43 (Cx43) half-channel blocker.

NP213 TFA is a rapidly acting and first-in-class synthetic antimicrobial peptide (AMP) with anti-fungal activity. It targets the fungal cytoplasmic membrane via membrane perturbation and disruption.

PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.

[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ET

BNP-45 (rat) TFA is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.