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ανβ5

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4153
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    2
    TargetMol | inventory
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    182
    TargetMol | natural
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    3
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    188
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    329
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    709
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    565
    TargetMol | inventory
5-Ph-IAA
T8885168649-23-8
5-Ph-IAA, a derivative of Indole-3-acetic acid (IAA), acts as a plant hormone and serves as an enzyme or prodrug combination for cancer gene therapy.
  • $58
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5-A-RU hydrochloride
T10165L134452-11-2In house
5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prostate cancer.
  • $1,320
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TargetMol | Inhibitor Hot
6-Diazo-5-oxo-L-nor-Leucine
T8373157-03-9
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.
  • $40
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Bis(2-methoxy-5-((Z)-3,4,5-trimethoxystyryl)phenyl) hydrogen phosphate
T67906735261-22-0In house
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.
  • $60
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5-HT6/7 antagonist 1
T61807131999-28-5In house
5-HT6 7 antagonist 1 is a dual 5-HT6 7 2A and D2 receptor antagonist used in the study of dementia and Alzheimer's disease.
  • $700 TargetMol
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1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)
T67696426242-86-6In house
1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea is a chemical compound.
  • $197
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(Rel)-Factor B-IN-5
T626892760789-22-6In house
Factor B-IN-5 is a potent inhibitor (IC50: 1.2 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.
  • $2,140
1-2 weeks
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Quilseconazole Formic acid(1340593-70-5 Free base)
T16704L In house
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
  • $169
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CCR2 antagonist 5
T276821228650-83-6In house
CCR2 antagonist 5 (JNJ-41443532) is a selective and orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM).JNJ-41443532 binds mCCR2 with a Ki of 9.6 µM, which can be used to study inflammatory diseases and diabetes. diseases and diabetes.
  • $110
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DENV-IN-5
T631432375781-06-7In house
Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.
  • $470
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Thalidomide 5-fluoride
T9381835616-61-0
Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1.
  • $29
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5-Hydroxy-1-methylhydantoin
T2822284210-26-4
5-Hydroxy-1-methylhydantoin (HD-003) is an antioxidant potentially for the treatment of renal failure. A creatinine metabolite, 5-Hydroxy-1-methylhydantoin , a hydroxyl radical scavenger, has previously been shown to confer renoprotection by inhibiting the progression of chronic kidney disease in rats. 5-Hydroxy-1-methylhydantoin is a novel anti-oxidant drug completely suppressed the expression of B2-kinin receptors (B2KR) in response to high glucose (25 mM) stimulation in VSMC and was also shown to attenuate the effects of BK on VSMC remodeling. 5-Hydroxy-1-methylhydantoin inhibited the BK-induced increase in MAPK phosphorylation and attenuated the increase in connective tissue growth factor (CTGF) protein levels in VSMC. These findings suggest that 5-Hydroxy-1-methylhydantoin may confer vascular protection against high glucose concentrations and BK-stimulation to ameliorate vascular injury and remodeling through its anti-oxidant properties.
  • $89
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Adenosine 5'-monophosphate disodium salt
T659794578-31-8
Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5'-monophosphate disodium salt has been shown to have a variety of biochemical and physiological effects. It has been shown to increase cell metabolism, gene expression, and protein synthesis.
  • $39
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Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride
T650862746-19-2
Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride may cause sensitization. Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride promotes apoptosis in HepG2 (IC50= 62 μM) and SK-Hep1 (IC50= 151 μM) cells and inhibits protein phosphatase 2A.
  • $29
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5-Aminovaleric acid
T5089660-88-8
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction: L-lysine leads to cadverine leads
  • $29
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5-Bromouracil
T806051-20-7
5-Bromouracil disrupts nucleosome positioning by inducing A-form-like DNA.
  • $29
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2,3-Dihydrobenzofuranyl-5-acetic acid
T135969999-16-2
2,3-Dihydro-5-benzofuranacetic Acid is used as Pharmaceutical material and intermeidates.
  • $29
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2,4-Dihydroxypyrimidine-5-carboxylic acid
T471123945-44-0
2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. 2,4-Dihydroxypyrimidine-5-carboxylic acid has been used to synthesize N1-alkylated uracil derivatives.
  • $35
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2,3,4-Trifluoro-5-Nitro-Benzoic Acid
T9438197520-71-1
2,3,4-Trifluoro-5-Nitro-Benzoic Acid is a useful intermediate in organic synthesis. It has been used to study the effect of fluorine substitution on the reactivity of organic molecules. It has also been used to study the effect of nitro substitution on the reactivity of organic molecules.
  • $30
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5-Amino-3H-imidazole-4-Carboxamide
T1705360-97-4
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
  • $29
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3-Amino-5-methylisoxazole
T06441072-67-9
3-Amino-5-methylisoxazole is pharmaceutical intermediates, used in the production of sulfonamide drugs.
  • $34
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Uridine-5'-diphosphate disodium salt
T470627821-45-0
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.
  • $32
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5-alpha-Hydroxy-Laxogenin
T2125356786-63-1
5-alpha-Hydroxy-Laxogenin is an stress hormone cortisol inhibitor
  • $41
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GSK-3 Inhibitor 5
T7755420099-89-2
GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) is a ketone derivative that is used as an intermediate in pharmaceuticals and organic synthesis, and inhibits glycogen synthase kinase 3 (GSK-3).
  • $29
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5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
T936126166-92-7
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthetic compound. It has been used as a catalyst and as a tool in enzyme kinetic studies; it has also been used in studies of enzyme inhibition, as well as in drug receptor interaction studies.
  • $30
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5-Methyl-2-thiophenecarboxaldehyde
T1915413679-70-4
5-Methyl-2-thiophenecarboxaldehyde is a candidate microscopic third-order nonlinear optical (NLO) material.5-Methyl-2-thiophenecarboxaldehyde possesses a wide range of biological activities, such as anticancer activity.
  • $45
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5-Chlorovaleronitrile
T204566280-87-1
5-Chlorovaleronitrile (AI320151) can be used as a quantitative structure-toxicity model to predict the aquatic toxicity.
  • $29
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5-Bromo-5-nitro-1,3-dioxane
T1980830007-47-7
5-Bromo-5-nitro-1,3-dioxane (Bronidox) is an antimicrobial compound that inhibits bacterial enzyme activity.
  • $30
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5-Methyluridine
T52821463-10-1
5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents.
  • $41
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5-Methylcytosine
T5270554-01-8
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. It is an epigenetic modification formed by the action of DNA methyltransferases.
  • $33
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5-Ethynyl-2'-deoxyuridine
T1734161135-33-9
5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.
  • $33
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TargetMol | Citations Cited
Pyridoxal 5'-phosphate monohydrate
T808341468-25-1
Quinaldic acid is an endogenous metabolite.Quinaldic acid is a metal chelator.
  • $29
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5'-Guanylic acid disodium salt
T49015550-12-9
5'-Guanylic acid disodium salt (GMP-5) is a purine ribonucleoside monophosphate. L-Glutamic acid and guanosine monophosphate are biosynthesized from xanthylic acid and L-glutamine via GMP synthase [glutamine-hydrolyzing]. Guanosine triphosphate and guanosine monophosphate are biosynthesized from diguanosine tetraphosphate via bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin, telithromycin, tobramycin, and erythromycin action pathways, and several metabolic disorders including AICA-ribosiduria, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and 2-hydroxyglutric aciduria (D and L form) pathways. Guanosine monophosphate is also found in foods like onion-family vegetables, millet, Chinese water chestnut, and red rice, serving as a potential biomarker for the consumption of these foods.
  • $41
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TargetMol | Citations Cited
2'-Hydroxy-5'-methoxyacetophenone
T3760705-15-7
2'-Hydroxy-5'-methoxyacetophenone (5-Methoxy-2-hydroxyacetophenone) is an active biochemical.
  • $29
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Uridine 5'-monophosphate disodium salt
TMA24403387-36-8
Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.
  • $30
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5-Methoxysalicylic acid
T58882612-02-4
5-Methoxysalicylic acid (5-MeOSA), a natural product, serves as an effective matrix for oligonucleotide analysis in MALDI MS when used alongside spermine.
  • $29
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5-Methoxyindole-3-acetic acid
T135133471-31-6
5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
  • $42
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5-Fluorouridine
T1349316-46-1
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.
  • $39
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TargetMol | Citations Cited
5-Azacytidine
T1339320-67-2
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autophagy and has antitumor activity.
  • $33
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TargetMol | Citations Cited
5-Methylfurfural
TCP2934620-02-0
5-Methylfurfural (5-Methyl-2-furaldehyde) has been identified as one of the volatile flavor compounds in tamarind, Dutch Coffee, barrel-aged wines and deep fat-fried soybeans.
  • $29
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Guanosine 5'-diphosphate
T7210146-91-8
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6 Stat-3 Pathway.
  • $37
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Adenosine 5'-diphosphate sodium salt
T507920398-34-9
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
  • $30
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5-Methoxyuridine
TNU012335542-01-9
5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.5-Methoxyuridine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.
  • $35
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5-Fluorouracil
T098451-21-8
5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.
  • $30
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TargetMol | Citations Cited
5-Aminothalidomide
T40017191732-76-0
5-Aminothalidomide is a E3 ligase ligand used in PROTAC technology.
  • $39
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Guanosine-5'-triphosphate disodium salt
T1151156001-37-7
Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and serves as an energy source for translation and other critical cellular processes.
  • $56
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N-Acetyl-5-hydroxytryptamine
T13541210-83-9
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to melatonin by acetylserotonin O-methyltransferase. It can potently activate TrkB receptor.
  • $32
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Guanosine 5'-diphosphate disodium salt
T76067415-69-2
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6) stat-3 pathway.
  • $30
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