αhydroxyglutaric acid

α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synthase and mTOR signaling.

α-Hydroxyglutaric Acid is a natural product for research related to life sciences. The catalog number is T36624 and the CAS number is 2889-31-8.This compound is unstable in powder form and other related salt forms are recommended.

D-α-Hydroxyglutaric acid is a natural product for research related to life sciences. The catalog number is T41318 and the CAS number is 13095-47-1.

L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Additionally, it obstructs histone demethylases, thereby encouraging histone methylation.

L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively).

DL-alpha-Hydroxyglutaric acid disodium salt is an alpha-ketoglutarate (α-KG) antagonist that inhibits a variety of α-KG-dependent dioxygenases.

3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.

D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.

DL-α-Hydroxyglutaric acid disodium salt-d4 is a deuterated compound of DL-α-Hydroxyglutaric acid disodium salt. DL-α-Hydroxyglutaric acid disodium salt has a CAS number of 40951-21-1. DL-α-Hydroxyglutaric acid disodium salt is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran carboxylic acid, which is overproduced in human neurometabolic disease D-α -hydroxyglutaric uria.