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Search Results for " glyt "

Targets

8

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T11908 LY2365109 hydrochloride GlyT
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
T9833 Opiranserin hydrochloride P2X Receptor , GlyT , 5-HT Receptor
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50...
T6788 Bitopertin Paliflutine,RO4917838,RG1678 GlyT
Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.
T11435 GlyT1 Inhibitor 1 Others
GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor (IC50: 38 nM for rGlyT1) with antipsychotic activity.
T16399 Opiranserin P2X Receptor , GlyT , 5-HT Receptor
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) an...
T28260 Org-25935 Org 25935,SCH-900435,SCH 900435
Org-25935, a GlyT-1 inhibitor, is used potentially for the treatment of schizophrenia and alcohol dependence.
T37700 Org 24598 lithium salt
Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1. Org 24598 lithium salt inhibits the specific binding of [3H]CHIBA-3007 to rat meninges (Ki=16.9 nM).
T37699 Org 24598
Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transport...
Cat No. Product Name Synonyms Targets
T6975 Sarcosine Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine Others , GlyT , Endogenous Metabolite
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
TargetMol