abemaciclib metabolite m-2

β2AR/M-receptor agonist-2 is a dual-function compound acting as a muscarinic antagonist and β2 adrenoceptor agonist (MABA). It demonstrates significant activity towards the β2 adrenoceptor with an EC50 of 3.7 nM and exhibits affinity for the human cloned M3 receptor with a Ki of 0.73 nM. This potent bronchodilator holds potential for research in chronic obstructive pulmonary disease (COPD) treatment.

Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer.

M-MoDE-A (2) is a bifunctional small molecule that facilitates the degradation of extracellular proteins via the asialoglycoprotein receptor (ASGPR).

Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. It has been incorporated alongside a cereblon (CRBN) ligand to develop a proteolysis-targeting chimera (PROTAC) that selectively degrades CDK4/6 [1] [2].

m-PEG6-2-methylacrylate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-Dioxan-5-amine, 2-(p-chlorophenyl)- is a bioactive chemical.

Benzaldehyde, m-hydroxy-, (5-nitro-2-pyridyl)hydrazone is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-morpholinoethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-heptyloxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

Carbanilic acid, m-ethoxy-N-phenyl-, 2-(diethylamino)ethyl ester is a bioactive chemical.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-alpha,alpha,alpha-trifluoro-, hydrochloride is a bioactive chemical.

m-Dioxan-5-amine, 2-(p-chlorophenyl)-5-methyl- is a bioactive chemical.

m-Dioxan-5-amine, 2-(3,4-dichlorophenyl)-5-methyl- is a bioactive chemical.

2-Hexyl-m-cresol is a bioactive chemical.

m-Acetanisidide, 2-iodo- is a bioactive chemical.

(R)-2-Amino-3-(m-tolyl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65696 and the CAS number is 114926-39-5.

m-Acetotoluidide, 2-fluoro-N-methyl- is a bioactive chemical.

Aniline, m-(2-(2-(diethylamino)ethoxy)ethyl)- is a bioactive chemical.

Acetamide, 2-(p-butoxyphenoxy)-N-(2-(dimethylamino)ethyl)-N-(m-ethoxyphenyl)-, hydrochloride is a bioactive chemical.

m-Acetanisidide, 2-chloro-N-(2-ethoxyethyl)- is a bioactive chemical.

m-Acetotoluidide, 6'-chloro-2-(2-(diethylamino)ethyl)methylamino-, dihydrochloride is a bioactive chemical.

Phenol, m-(2-(methylamino)ethyl)-, hydrochloride is a biaoctive chemical.

Benzoic acid, m-(2-(p-bromophenyl)-5-methylpyrrol-1-yl)- is a bioactive chemical.

m-Dioxane, 5-isopropyl-5-(1-methoxyethyl)-2-methyl-, (E)- is a bioactive chemical.

Carbanilic acid, m-hydroxy-, 2-methoxyethyl ester, methylcarbamate is a bioactive chemical.

Carbanilic acid, m-((pentyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

Benzoic acid, m-(2-methyl-5-phenylpyrrol-1-yl)-, compd. with 2-amino-2-methyl-1-propanol (1:1) is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(1-methyl-2-piperidino)ethyl- is a bioactive chemical.

4-Chloro-2-nitro-m-cresol is a biaoctive chemical.

m-Anisidine, 4-(2-ethylbutoxy)-, hydrobromide is a bioactive chemical.

Lopinavir Metabolite M-1, an active metabolite derived from Lopinavir, effectively inhibits the HIV protease enzyme with a Ki value of 0.7 pM. Additionally, in vitro studies have revealed notable antiviral properties associated with Lopinavir Metabolite M-1.

Benzoic acid, m-(2-methyl-5-phenylpyrrol-1-yl)- is a bioactive chemical.

Benzoic acid, m-(2-methyl-5-phenylpyrrol-1-yl)-, compd. with 2-aminoethanol (1:1) is a bioactive chemical.

Benzylamine, m-chloro-N-(2-chloroethyl)-N-ethyl-, hydrochloride is a bioactive chemical.

Benzoic acid, m-iodo-, 2-phenylhydrazide is a bioactive chemical.

m-Dioxan-5-amine, 5-benzylaminomethyl-2-phenyl- is a bioactive chemical.

m-Acetotoluidide, N-benzyl-2-(diethylamino)-, monohydrochloride is a bioactive chemical.

Carbanilic acid, m-ethoxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.

Carbanilic acid, m-hexyloxy-, 2-piperidinocyclohexyl ester, hydrochloride, (E)- is a bioactive chemical.

m-Acetophenetidide, 2-iodo- is a bioactive chemical.

Carbanilic acid, m-heptyloxy-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

m-Acetotoluidide, 2-chloro-N-(2-ethoxyethyl)- is a bioactive chemical.

Phenol, m-(2-(dipropylamino)ethyl)-, hydrobromide is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(diethylamino)ethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-(hexahydro-1H-azepin-1-yl)ethyl ester, hydrochloride is a bioactive chemical.

Carbanilic acid, m-ethoxy-N-phenyl-, 2-(dimethylamino)ethyl ester is a bioactive chemical.

Phenol, m-(2-ethyl-1-methyl-3-propyl-3-pyrrolidinyl)-, acetate is a bioactive chemical.

m-Acetophenetidide, 2-chloro- is a bioactive chemical.