acid-peg5-mono-methyl ester

Acid-PEG5-mono-methyl ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Benzyl-PEG3-methyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker employed for the synthesis of PROTACs, serving as an integral compound[1].

4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) that can be cleaved.

m-PEG4-CH2-methyl ester is a polyethylene glycol (PEG)- and Alkyl/ester-based linker utilized in the fabrication of proteolysis targeting chimeras (PROTACs) [1].

Acid-PEG4-mono-methyl ester, a PEG- and Alkyl/ether-based PROTAC linker, can be employed for PROTAC synthesis[1].

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker employed in PROTAC synthesis[1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].

Hydroxy-PEG2-C2-methyl ester is a polyethylene glycol (PEG)-based linker commonly employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Active-mono-sulfone-PEG8-acid is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis[1].

Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a linker; notably, one ligand interacts with the VHL portion.

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis. It is specifically designed for the creation of proteolysis-targeting chimeras (PROTACs)[1].

Thiol-PEG3-phosphonic acid ethyl ester, a PEG-based linker, serves as a valuable component in the synthesis of PROTACs[1].

Hydroxy-PEG5-C2-methyl ester is a polyethylene glycol (PEG) derived linker compound employed in PROTAC (PROteolysis TArgeting Chimeras) synthesis[1].

Acid-PEG3-mono-methyl ester, an alkyl/ether-based PROTAC linker, facilitates the synthesis of PROTACs[1].

5-endo-BCN-pentanoic acid, an alkyl chain-based PROTAC linker, facilitates the synthesis of PROTACs[1].

m-PEG4-C6-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based linker compound utilized for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG4-CH2-methyl ester is a PEGylated linker compound utilized for the synthesis of PROTACs.

Bromo-PEG2-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

3-Mercaptopropionic acid NHS ester is a useful organic compound for research related to life sciences and the catalog number is T64663.

PEG2-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative commonly employed as a linker in proteolysis-targeting chimeras (PROTACs) synthesis[1].

Acid-C2-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Aminooxy-PEG3-methyl ester, a PEG-based PROTAC linker, serves as a pivotal element in the synthesis of PROTACs[1].

m-PEG8-(CH2)12-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based PROTAC linker, suitable for the synthesis of PROTAC compounds[1].

S-acetyl-PEG3-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Acid-C2-PEG4-C2-NHS ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Acid-PEG9-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-Lys-NHS ester (MW 20000) is an alkyl/ether-based PROTAC linker commonly employed in PROTAC synthesis[1].

m-PEG9-phosphonic acid ethyl ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Tos-PEG3-C2-methyl ester is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

m-PEG-NHS ester (MW 5000) serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

m-PEG6-C6-phosphonic acid ethyl ester serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

Fmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Azido-PEG4-(CH2)3-methyl ester is a polyethylene glycol (PEG) based linker utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Propargyl-PEG3-methyl ester is a propargyl polyethylene glycol (PEG) derivative that serves as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Azido-PEG1-methyl ester is an alkyl/ether-based linker employed for the synthesis of PROTACs[1].

5-Maleimidovaleric acid, a cleavable linker for antibody-drug conjugates (ADCs) synthesis, is employed as an ADC linker[1].

Propargyl-PEG3-phosphonic acid diethyl ester, a PEG-based PROTAC linker, is employed for the synthesis of PROTACs[1].

Acid-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-cis-4-hydroxy-D-proline methyl ester is a useful organic compound for research related to life sciences. The catalog number is T66907 and the CAS number is 114676-69-6.

6-Maleimidocaproic acid-PFP ester is a hydrocarbon-based PROTAC linker, suitable for the synthesis of PROTACs[1].

C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-derived PROTAC linker suitable for PROTAC synthesis[1].

Hydroxy-PEG3-C2-methyl ester is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

m-PEG5-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-derived linker commonly employed in the construction of proteolysis targeting chimeras (PROTACs)[1].

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker for the design and synthesis of PROTACs, which are heterobifunctional molecules facilitating targeted protein degradation[1].

Bromo-PEG3-phosphonic acid diethyl ester is a polyethylene glycol (PEG) derivative commonly employed as a linker for the assembly of proteolysis targeting chimeras (PROTACs)[1].