active mono sulfone peg8 acid

Active-mono-sulfone-PEG8-acid, a polyethylene glycol (PEG) derivative, serves as a linker for PROTAC synthesis [1].

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.

Biotin-PEG8-acid is a PEG-based PROTAC linker labeled with biotin, utilized in PROTAC synthesis.

endo-BCN-PEG8-acid, a PEG-based linker, is pivotal for PROTAC molecules, connecting two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Sulfone-Bis-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG3-Sulfone-PEG4-acid, a polyethylene glycol (PEG) derivative, is frequently employed as a linker in the construction of proteolysis targeting chimeras (PROTACs) [1].

Acid-PEG8-S-S-PEG8-acid, a PEG-based linker for PROTACs, joins two essential ligands vital for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methyltetrazine-PEG8-acid is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Cbz-aminooxy-PEG8-acid is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Acid-PEG4-mono-methyl ester, a PEG- and Alkyl ether-based PROTAC linker, can be employed for PROTAC synthesis[1].

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Acid-PEG6-mono-methyl ester is a polyethylene glycol (PEG)-based PROTAC linker suitable for the synthesis of PROTACs [1].

TCO-PEG8-acid, a PEG-based linker for PROTACs, joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Aminooxy-PEG8-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Thiol-PEG8-acid, a PEG-based linker for PROTACs, facilitates the conjugation of two essential ligands necessary for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-(m-PEG8-amido)-hexanoic acid is a polyethylene glycol (PEG)-based linker used in synthesizing proteolysis targeting chimeras (PROTACs) [1].

Acid-PEG5-mono-methyl ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

m-PEG8-ethoxycarbonyl-propanoic acid, a PEG-derived PROTAC linker, is employed for the synthesis of PROTACs[1].

Mal-PEG8-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG8-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs and antibody-drug conjugates (ADCs)[1]. It serves as a cleavable ADC linker, facilitating the development of specialized compounds.

Mal-amido-PEG8-C2-acid (US2018339985, example 142) is a noncleavable linker for antibody-drug conjugates (ADCs) [1].

Acid-PEG3-mono-methyl ester, an alkyl ether-based PROTAC linker, facilitates the synthesis of PROTACs[1].

DBCO-PEG8-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG8-acid is a non-cleavable 8-unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Lipoamido-PEG8-acid is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG8-(CH2)12-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based PROTAC linker, ideal for synthesizing PROTAC compounds[1].

Bromoacetamido-PEG8-acid, a PEG-derived PROTAC linker, is suitable for synthesizing PROTACs[1].

Cbz-NH-PEG8-C2-acid is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1].

m-PEG3-Sulfone-PEG3-acid is a polyethylene glycol (PEG)-based linker used in protein degradation via targeted chimera (PROTAC) [1].

m-PEG8-C10-phosphonic acid is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation via the ubiquitin-proteasome system within cells [PROTACs].

Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

The compound 3,4-Dibromo-Mal-PEG8-acid is a PEG-based PROTAC linker employed for PROTAC synthesis[1].