ald-ph-amido-peg-2

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugates (ADCs)[1].

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Ald-Ph-amido-PEG2-C2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies and drugs.

Ald-Ph-amido-PEG2-C2-NHS ester is a non-cleavable, 2-unit PEG linker used in antibody-drug conjugation (ADC) for attaching antibodies to drugs.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs [1].

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used in the development of antibody-drug conjugates (ADCs).

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

Ald-Ph-PEG2-Boc is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound comprising a cereblon (CRBN) ligand that functions as an E3 ubiquitin ligase, along with a linker. It is utilized to create the PROTAC MD-224[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs[1].

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

Ald-Ph-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG6-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used in the development of antibody-drug conjugates (ADC).

Ald-Ph-PEG24-TFP ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG3-C1-Boc is a polyethylene glycol (PEG) linker used specifically in antibody-drug conjugates (ADC).

Ald-Ph-amido-PEG23-OPSS is a cleavable, 23-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in the synthesis of PROTACs[1].

Ald-Ph-amido-PEG1-C2-NHS ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Ald-Ph-PEG6-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Ald-Ph-amido-PEG24-acid, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Ald-Ph-PEG5-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enables selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative mainly used as a noncleavable ADC linker[1].

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Ald-Ph-PEG12-TFP ester is a PEG-based linker for PROTACs that connects two essential ligands, playing a crucial role in the formation of PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable, 4-unit PEG linker used in antibody-drug conjugation (ADC) to attach antibodies to drugs.

Mal-amido-(CH2COOH)2, also known as compound 7a, is an intermediate compound that contains maleimidoethyl for use in hydrophilic ADC linker synthesis[1].

Ald-Ph-amido-PEG3-C2-Pfp ester is a noncleavable antibody-drug conjugate (ADC) linker, classified as a polyethylene glycol (PEG) linker.

Ald-Ph-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the [ubiquitin-proteasome] system within cells.

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.