ald-ph-amido-peg23-opss

Ald-Ph-amido-PEG23-OPSS is a cleavable, 23-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

Ald-Ph-PEG12-TFP ester is a PEG-based linker for PROTACs that connects two essential ligands, playing a crucial role in the formation of PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable, 4-unit PEG linker used in antibody-drug conjugation (ADC) to attach antibodies to drugs.

Ald-Ph-amido-PEG3-C2-Pfp ester is a noncleavable antibody-drug conjugate (ADC) linker, classified as a polyethylene glycol (PEG) linker.

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG24-acid, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Ald-Ph-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the [ubiquitin-proteasome] system within cells.

Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Ald-Ph-amido-PEG2-C2-NHS ester is a non-cleavable, 2-unit PEG linker used in antibody-drug conjugation (ADC) for attaching antibodies to drugs.

Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative mainly used as a noncleavable ADC linker[1].

Ald-Ph-PEG5-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enables selective protein degradation through the ubiquitin-proteasome system within cells.

Tetrazine-Ph-OPSS is an ADC linker employed for synthesizing ADCs, or antibody-drug conjugates [1].

Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound comprising a cereblon (CRBN) ligand that functions as an E3 ubiquitin ligase, along with a linker. It is utilized to create the PROTAC MD-224[1].

Ald-Ph-PEG2-Boc is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used in the development of antibody-drug conjugates (ADCs).

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs [1].

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies and drugs.

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used in the development of antibody-drug conjugates (ADC).

Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

Ald-Ph-PEG24-TFP ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG3-C1-Boc is a polyethylene glycol (PEG) linker used specifically in antibody-drug conjugates (ADC).

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Ald-Ph-amido-PEG1-C2-NHS ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Ald-Ph-amido-C2-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-PEG6-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG6-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugates (ADCs)[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.