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Results for "

alkyne-peg-4-ss-peg4-alkyne

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3401
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Alkyne-PEG4-SS-PEG4-alkyne
T17386
Alkyne-PEG4-SS-PEG4-alkyne is an eight-unit polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis, enabling cleavage and controlled drug release under specific conditions [1].
  • Inquiry Price
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QTY
Thalidomide 4-fluoride
T7755835616-60-9
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
N-Boc-4-pentyne-1-amine
T18391151978-50-6
N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].
  • $50
In Stock
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QTY
TargetMol | Inhibitor Sale
Thalidomide-4-OH
T77635054-59-1
Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs
  • $29
In Stock
Size
QTY
DSPE-PEG-OH (MW 2000)
T17854
DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.
  • $133
In Stock
Size
QTY
PC Biotin-PEG3-alkyne
T164371869922-24-6
PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).
  • $321
In Stock
Size
QTY
Pomalidomide 4'-alkylC3-acid
T400262225940-47-4
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid) is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.
  • $55
In Stock
Size
QTY
m-PEG7-4-nitrophenyl carbonate
T15919678150-56-6
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker used in PROTAC synthesis [1].
  • $65
In Stock
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QTY
BSJ-4-116
T91172519823-34-6
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
  • $50
In Stock
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TargetMol | Citations Cited
Amine-PEG-CH2COOH (MW 2000)
T17397
Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
  • $29
In Stock
Size
QTY
Thalidomide 4'-ether-alkylC2-amine hydrochloride
T400302341840-99-9
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.
  • $50
In Stock
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QTY
TargetMol | Inhibitor Sale
m-PEG8-O-alkyne
T18222880081-81-2
m-PEG8-O-alkyne is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (proteolysis-targeting chimeras).
  • $48
In Stock
Size
QTY
TargetMol | Inhibitor Sale
N-Boc-4-hydroxy-L-proline methyl ester
FL0195102195-79-9
N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].
  • Inquiry Price
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Pomalidomide 4'-PEG2-azide 
T93872271036-45-2
Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate, comprising a Pomalidomide-based cereblon ligand and a linker.
  • $44
In Stock
Size
QTY
Thalidomide 4'-ether-PEG3-amine
T36249
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
  • $259
Backorder
Size
QTY
TBK1 control PROTAC® 4
T362472052306-31-5
Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
  • $1,070
35 days
Size
QTY
TargetMol | Inhibitor Sale
Dde Biotin-PEG4-alkyne
T150831802908-00-4
Dde Biotin-PEG4-alkyne is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
  • $331
5 days
Size
QTY
TargetMol | Inhibitor Sale
N-(4-Carboxycyclohexylmethyl)maleimide
T1616764987-82-2
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker suitable for synthesizing PROTACs [1].
  • Inquiry Price
7-10 days
Size
QTY
Azide-PEG-azide (MW 20000)
T17462
Azide-PEG-azide (MW 20000) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
  • Inquiry Price
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QTY
m-PEG-NHS ester (MW 5000)
T18104
m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].
  • Inquiry Price
5 days
Size
QTY
TargetMol | Inhibitor Sale
Azide-PEG-amine (MW 3500)
T17458
Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) linker compound, designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].
  • Inquiry Price
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Lenalidomide-4-aminomethyl
T40897790652-68-5
Lenalidomide-4-aminomethyl is a CRBN ligand derived from Lenalidomide, which is utilized for the recruitment of CRBN protein. By linking Lenalidomide-4-aminomethyl to the ligand, a PROTAC can be formed.
  • $1,520
Backorder
Size
QTY
Amine-PEG-amine (MW 3400)
T17392
Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
  • Inquiry Price
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PROTAC ER Degrader-4
T138392361114-15-8
PROTAC ER Degrader-4 is a PROTAC degrader of the estrogen receptor (ER) with an IC50 of 0.8 nM.
  • Inquiry Price
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m-PEG-CH2COOH (MW 2000)
T18087
m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].
  • Inquiry Price
Size
QTY
PROTAC BRD9 Degrader-4
T779362633632-34-3
PROTAC BRD9 Degrader-4 is a bifunctional degrader that targets BRD9, specifically designed for applications in cancer research.
  • Inquiry Price
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Acrylate-PEG-OH (MW 5000)
T17362
Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis [1].
  • Inquiry Price
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QTY
Pomalidomide 4'-alkylC6-azide
T849032375555-72-7
Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1].
  • Inquiry Price
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Biotin alkyne
T66674
Biotin alkyne is a useful organic compound for research related to life sciences and the catalog number is T66674.
    7-10 days
    Inquiry
    PROTAC CDK9 degrader-4
    T399962411021-01-5
    PROTAC CDK9 degrader-4 is a potent and efficacious compound designed to degrade CDK9, a protein involved in transcription regulation, thereby modulating transcriptional activity by effectively targeting and reducing CDK9 levels.
    • Inquiry Price
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    Amine-PEG-thiol (MW 5000)
    T17400
    Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].
    • Inquiry Price
    Size
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    PROTAC AR Degrader-4 TFA
    T73726
    PROTAC AR Degrader-4, an Androgen Receptor (AR) degrader, incorporates an IAP ligand binding group, a linker, and an AR binding group. It represents a class of degradation inducers known as specific and non-genetic IAP-dependent protein erasers (SNIPERs) [1], operating through a mechanism involving cIAP1.
    • Inquiry Price
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    Aminooxy-PEG-OH (MW 2000)
    T17446
    Aminooxy-PEG-OH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].
    • Inquiry Price
    Size
    QTY
    Amine-PEG-CH2COOH (MW 3400)
    T17396
    Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).
      Inquiry
      Amine-PEG-amine (MW 35000)
      T17393
      Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].
      • Inquiry Price
      Size
      QTY
      Thiol-PEG-CH2COOH (MW 5000)
      T18834
      Thiol-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derivative frequently used in the construction of PROTACs, bifunctional compounds designed for targeted protein degradation [1].
      • Inquiry Price
      Size
      QTY
      m-PEG-triethoxysilane (MW 2000)
      T18115
      m-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG)-based linker compound tailored for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
      • Inquiry Price
      Size
      QTY
      Mal-PEG-mal (MW 3400)
      T18264
      Mal-PEG-mal (MW 3400) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system in cells.
      • Inquiry Price
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      Tetrazine-Ph-NHCO-PEG4-alkyne
      T18796
      Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG4-based linker used in PROTACs synthesis [1].
      • Inquiry Price
      Size
      QTY
      m-PEG-Lys-NHS ester (MW 20000)
      T18090
      m-PEG-Lys-NHS ester (MW 20,000) is an alkyl ether-based PROTAC linker commonly used in PROTAC synthesis[1].
      • Inquiry Price
      Size
      QTY
      Biotin-PEG-triethoxysilane (MW 1000)
      T17553
      Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].
      • Inquiry Price
      Size
      QTY
      m-PEG-acrylate (MW 2000)
      T18078
      m-PEG-acrylate (MW 2000) is a polyethylene glycol (PEG) derivative linker that plays a crucial role in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
      • Inquiry Price
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      (S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl
      T179121835705-61-7
      (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].
      • $61
      5 days
      Size
      QTY
      m-PEG-triethoxysilane (MW 1000)
      T18114
      m-PEG-triethoxysilane (MW 1000) is a triethoxysilane-functionalized polyethylene glycol (PEG) derivative that serves as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs), which are compounds used for targeted protein degradation[1].
      • Inquiry Price
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      cis-4-Hydroxy-D-proline hydrochloride
      T6693377449-94-6
      cis-4-Hydroxy-D-proline hydrochloride (catalog number T66933, CAS number 77449-94-6) is a valuable organic compound for research in life sciences.
        7-10 days
        Inquiry
        Diazo Biotin-PEG3-alkyne
        T151141884349-58-9
        Diazo Biotin-PEG3-alkyne is a polyethylene glycol (PEG)-based linker designed specifically for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
        • $90
        In Stock
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        D-Proline, 4-hydroxy-, methyl ester hydrochloride
        T65606114676-59-4
        D-Proline, 4-hydroxy-, methyl ester hydrochloride (T65606, CAS 114676-59-4) is a valuable organic compound for life sciences research.
          7-10 days
          Inquiry
          PROTAC IRAK4 degrader-4
          T399012360528-45-4
          PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
          • Inquiry Price
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          m-PEG-NH2 (MW 2000)
          T18099
          m-PEG-NH2 (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
          • Inquiry Price
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          QTY
          Methyltetrazine-PEG5-alkyne
          T160591802907-97-6
          Methyltetrazine-PEG5-alkyne, a PEG-based PROTAC linker, is utilized in synthesizing PROTACs[1].
          • Inquiry Price
          7-10 days
          Size
          QTY