amine peg amine (mw 2000)

Amine-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in PROTAC synthesis, facilitating targeted protein degradation [1].

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

HO-PEG-amine (MW 2000) is a PEG-based linker essential for constructing PROTAC molecules. It connects two critical ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG) linker utilized in PROTAC synthesis[1].

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG)-derived linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

Propargyl-PEG3-amine is a PEG-based linker for PROTACs, connecting two essential ligands critical for PROTAC molecule formation. This linker facilitates selective protein degradation through the ubiquitin-proteasome system within cells.

cis VH 032, amine dihydrochloride ((S,S,S)-AHPC) is a negative control for the functionalized VHL ligand VH 032, amine .

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.

DBCO-amine is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent estrogen receptor (ER) antagonists, offering an innovative approach for endocrine therapy in breast cancer treatment.

Amino-PEG13-amine (H2N-PEG13-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker used in PROTAC synthesis.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a polyethylene glycol (PEG)-based linker frequently used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

TCO-SS-amine, a cleavable linker crucial in ADC synthesis, joins cytotoxic drugs to antibodies for precise delivery to target cells or proteins. Its cleavable nature ensures controlled drug release, optimizing the effectiveness of ADCs.

TCO-PEG-TCO (MW 5000) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

(S)-TCO-PEG3-amine is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

DSPE-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG)-based linker molecule specifically designed for synthesizing protein-targeting chimeras (PROTACs)[1].

Azido-PEG8-amine, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG12-amine (H2N-PEG12-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

m-PEG-mal (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-NH2 (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Acrylate-PEG-NH2 (MW 10000) is a polyethylene glycol (PEG)-based linker used in PROTAC synthesis.

Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties, serving as a PEG-based linker for PROTAC synthesis to facilitate the targeted degradation of proteins of interest.

m-PEG-mal (MW 2000) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-NH2 (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-NH2 (MW 1000) is a PEG-based linker for PROTACs that connects two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

m-PEG-acrylate (MW 20000), a PEG-based PROTAC linker, serves as a useful component in the synthesis of PROTACs[1].

Boc-amido-PEG9-amine is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Exo-BCN-PEG2-Boc-amine is a PEG derivative containing a BCN group and a Boc-protected amine. PEG Linkers and PEG derivatives may be useful in the development of antibody-drug conjugates.

DSPE-PEG-Amine (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker, serving as a crucial component in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

TCO-PEG4-amine is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the selective protein degradation by leveraging the ubiquitin-proteasome system within cells. [PROTACs]

m-PEG-Succinimidyl Succinate (MW 5000) is a polyethylene glycol (PEG)-based linker with succinimidyl succinate functionality, mainly used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

m-PEG36-amine, a PEG-based linker for PROTACs, facilitates the formation of PROTAC molecules by connecting two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.