amine peg3 biotin

Amine-PEG3-Biotin can be used as a signal amplification label.

Biotin-PEG-Thiol (MW 2000) is a pegylated compound with high affinity and specificity for streptavidin or antibiotin, capable of modifying biomolecules, proteins, peptides, and small molecular materials. It is commonly used in agent release research and the development of novel nanomaterials [1].

Biotin-PEG-Alk (MW 3400), a biotinylated polyethylene glycol (PEG) compound with an alkyne group, serves as a versatile click chemistry reagent. The biotin moiety acts as an enzyme cofactor desirable for protein labeling, PEG imparts hydrophilicity and aqueous solubility with minimal toxicity, and the alkyne (a type of acyclic hydrocarbon) facilitates efficient target binding by reacting with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Biotin-PEG3-benzophenone is a biotin-labeled benzophenone. Benzophenone serves as both an endogenous metabolite and a photosensitizer, implicated in DNA photodamage. It can lead to oxidation of nucleobases, formation of cyclobutane pyrimidine dimers, single-strand breaks, DNA-protein crosslinks, or abasic sites, potentially causing a variety of lesions in nucleosides, oligonucleotides, or DNA.

Biotin-PEG-azide (MW 2000) is a biotinylated polyethylene glycol (PEG) compound featuring an azide group. Biotin serves as an enzyme cofactor suitable for protein labeling. PEG, noted for its hydrophilicity and water solubility, exhibits low toxicity. The azide functionality is a reasonably effective leaving group that participates in copper-catalyzed reactions with alkynes, enhancing the binding efficiency to biotin's targets.

Biotin-PEG-Alk (MW 600) is a biotin-labeled, alkyne-functionalized polyethylene glycol used as a click chemistry reagent for protein, peptide, and oligonucleotide modification [1]. Featuring an alkyne group, it is intended for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.

Biotin-PEG-Alk (MW 10000) is a biotinylated polyethylene glycol (PEG) derivative with an alkyne group designed for click chemistry applications. Combining biotin, an enzyme co-factor used in protein labeling, with PEG, a hydrophilic, water-soluble, and low-toxicity polymer, the alkyne moiety enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azido-containing molecules, enhancing the efficiency of targeting biotin-binding entities.

Biotin-PEG-OH (MW 3400) is a polymer consisting of biotin and polyethylene glycol (PEG) units [1].

Biotin-PEG-Alk (MW 20000) is a biotin-labeled polyethylene glycol (PEG) derivative with a terminal alkyne group for efficient click chemistry applications. Biotin serves as an enzymatic cofactor, providing specific protein labeling, while the hydrophilic PEG moiety offers solubility and low toxicity. The alkyne functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing target binding through reaction with azide-modified molecules.

Biotin-PEG-azide (MW 3400) is a biotinylated polyethylene glycol (PEG) derivative featuring an azide group. Biotin functions as an enzyme co-factor for protein labeling, while PEG, a hydrophilic and water-soluble polymer with low toxicity, enhances solubility. The azide group, a moderately good leaving group, undergoes Cu-catalyzed reactions with alkynes, improving biotin's target binding efficiency.

Biotin-PEG-OH (MW 20000) is a polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs [1].

Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative with biotin labels at each terminal end. Biotin facilitates protein labeling as an enzyme co-factor, while the hydrophilic and low-toxicity nature of PEG imparts water solubility to the compound.

Biotin-PEG-Alk (MW 2000) is a biotin-labeled polyethylene glycol (PEG) derivative with an alkyne group for click chemistry applications. This compound efficiently binds to biotin targets via the alkyne moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAC) and enhancing biotin-avidin interaction assays in bioconjugation processes like protein labeling. The hydrophilic nature of PEG ensures solubility in aqueous environments and minimal toxicity.

Biotin-PEG-Alk (MW 1000) is a biotinylated polyethylene glycol (PEG) derivative featuring alkyne functionality for click chemistry applications. Biotin acts as an enzyme co-factor for protein labeling, while PEG imparts hydrophilic, water-soluble, low-toxicity properties. The alkyne group (Alk) enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with azido-modified molecules, enhancing targeting and binding with biotin receptors.