amino-peg-14-alcohol

Amino-PEG14-alcohol (H2N-PEG14-OH) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Amino-PEG9-alcohol is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras], facilitating the conjugation of two essential ligands for PROTAC formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amino-PEG12-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Amino-PEG12-alcohol is a PEG derivative containing an amino group with a hydroxyl group. PEG Linkers may be useful in the development of antibody-drug conjugates. The hydroxyl group enables further derivatization or replacement with other reactive functio

Amino-PEG36-alcohol is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG24-alcohol is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Amino-PEG4-alcohol is a PEG-based PROTAC linker used for synthesizing PROTACs[1] and a non-cleavable 4-unit PEG ADC linker for synthesizing antibody-drug conjugates (ADCs)[2].

Azide-PEG-alcohol, a polyethylene glycol (PEG)-based PROTAC linker with a molecular weight of 2000, functions as a versatile option for the synthesis of PROTACs[1].

14-(Fmoc-amino)-tetradecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. 14-(Fmoc-amino)-tetradecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.