amino-peg-9-alcohol

Amino-PEG9-alcohol is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras], facilitating the conjugation of two essential ligands for PROTAC formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amino-PEG14-alcohol (H2N-PEG14-OH) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Amino-PEG12-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Azide-PEG-alcohol, a polyethylene glycol (PEG)-based PROTAC linker with a molecular weight of 2000, functions as a versatile option for the synthesis of PROTACs[1].

9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Amino-PEG12-alcohol is a PEG derivative containing an amino group with a hydroxyl group. PEG Linkers may be useful in the development of antibody-drug conjugates. The hydroxyl group enables further derivatization or replacement with other reactive functio

Amino-PEG36-alcohol is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG24-alcohol is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amino-PEG4-alcohol is a PEG-based PROTAC linker used for synthesizing PROTACs[1] and a non-cleavable 4-unit PEG ADC linker for synthesizing antibody-drug conjugates (ADCs)[2].

Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].