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Results for "

angiotensin i/ii (1 6) (tfa)

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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Angiotensin I/II (1-6) (TFA)
T36622
Angiotensin I II (1-6) TFA is a chemical compound comprising amino acids 1-6, derived from the Angiotensin I II peptide. This peptide is formed by the cleavage of angiotensinogen by renin, with Angiotensin I subsequently hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].
  • $58
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Pam3CSK4 TFA (112208-00-1 free base)
TP1067112208-01-2
Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1 2 (TLR1 2) (EC50 of 0.47 ng mL for human TLR1 2).
  • $128
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Angiotensin II human
T70404474-91-3
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthesis and renal activity in humans.
  • $37
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Angiotensin 1/2 (1-9) TFA
T7663L
Angiotensin 1/2 (1-9)TFA is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
  • $50
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Rotigaptide TFA(355151-12-1 free base)
T16790L
Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.
  • $135
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Jagged-1 (188-204) TFA(219127-21-6 free base)
TP1293
Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
  • $235
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Angiotensin II 5-valine TFA
TP1017L
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.
  • $53
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Gastrin I (1-14), human
TP1705100940-57-6
Gastrin I (1-14), human, is the 1-14 peptide fragment of human gastrin I, an endogenous gastrointestinal peptide hormone, and is the primary hormonal regulator of gastric acid secretion.
  • $226
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pro-asp TFA(85227-98-1 free base)
TP2318
pro-asp TFA(85227-98-1 free base) (TLβ4) down-regulate skin inflammation in mouse skin.
  • $133
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2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
TP1378
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.
  • $50
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[Sar1, Ile8]-Angiotensin II acetate
T7575L1
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra
  • $37
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IGF-I 30-41 acetate(82177-09-1 free base)
TP1122L
IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).
  • $133
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JAG-1, scrambled TFA(402941-23-5 free base)
TP1686L
JAG-1, scrambled TFA is a scrambled sequence of JAG-1(188-204).
  • $93
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Urotensin II, mouse acetate (9047-55-6 free base)
TP2165
Urotensin II, mouse acetate (9047-55-6 free base) is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
  • $168
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Angiotensin I/II (1-5)
TP152858442-64-1
Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.
  • $50
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[Sar1, Ile8]-Angiotensin II 3TFA
T7575L
[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) is a peptide that has multiple effects on vascular smooth muscle.
  • $48
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β-amyloid 1-11 acetate(190436-05-6 free base)
TP1866L
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
  • $65
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Acth (1-4) acetate(19405-50-6 free base)
T20482L
Acth (1-4) acetate is the ACTH N-terminal tetrapeptide.
  • $133
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Allatostatin IV TFA(123338-13-6 free base)
TP1605L1
Allatostatin IV TFA, an octapeptide amine, is a member of the allatoregulatory peptide family found in insects which either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis.
  • $66
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Angiotensin 1/2 (5-7) acetate
T22574L
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It
  • $37
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FSLLRY-NH2 TFA(245329-02-6 free base)
TP1904L
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
  • $98
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CaM kinase II inhibitor TFA salt
TP1216
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
  • $177
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Nociceptin (1-13) amide TFA
TP1793L
Nociceptin (1-13), amide is a potent agonist Opioid receptor-like1 (ORL1) receptor with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.
  • $133
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Angiotensin I/II (1-6)
TP157947896-63-9
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
  • $50
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Biotin-β-Amyloid (1-42), human TFA
T80035
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the pathogenesis of Alzheimer's disease.
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740 Y-P(TFA)(1236188-16-1 free base)
TQ0003L
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
  • $96
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Angiotensin II human acetate
T856068521-88-0
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
  • $32
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Cardiotoxin Analog (CTX) IV (6-12) TFA
TP12892918768-05-3
Cardiotoxin Analog IV (6-12) TFA, a partial peptide of Cardiotoxin Analog IV, is derived from the venom of the Taiwan Cobra, showcasing the unique properties of snake venom cardiotoxin[1].
  • $45
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GLP-1(7-37) acetate(106612-94-6 free base)
TP13761450806-98-0
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
  • $113
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Angiotensin (1-7)
T733951833-78-4
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activities.
  • $33
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Angiotensin I (human, mouse, rat)
TP1295484-42-4
Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE). This peptide hormone causes vasoconstriction and increases blood pressure as part of the renin–angiotensin system, also stimulating aldosterone release from the adrenal cortex to promote sodium retention by the kidneys.
  • $57
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Fibrinopeptide B, human TFA (36204-23-6 free base)
TP1162
FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.
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IRBP (1-20) (human, rat) TFA
T83681
Interphotoreceptor retinoid-binding protein (1-20) (IRBP1-20), a dodecapeptide fragment of retinoid-binding protein 3, plays a crucial role in pigment regeneration by facilitating the transport of retinol and retinal between photoreceptor cells and the retinal pigment epithelium. It has been utilized to provoke autoimmune uveoretinitis in C57BL/6 mice, possessing the H-2b haplotype. Furthermore, IRBP1-20 at a concentration of 3 µM enhances the secretion of IL-4, IL-5, and IL-6 from primary mouse spleen lymphocytes. Immunization and subsequent rechallenge with IRBP1-20 lead to increased ear swelling, inflammation of ocular blood vessels, infiltration by immune cells, damage to the photoreceptor layer, and retinal detachment in IFN-γ-deficient mice.
  • $84
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Gastric Inhibitory Peptide 1 (3-42) (human) TFA
T83696
Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmol/kg to an ob/ob mouse diabetes model, GIP-1 (3-42) elevates plasma glucose levels and lowers plasma insulin levels, demonstrating its effect on reducing insulin secretion from BRIN-BD11 pancreatic cells at a concentration of 100 nM.
  • $76
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PAR2 (1-6) (mouse, rat)
T36531164081-25-8
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.
  • $110
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Super-TDU (1-31) TFA
TP1331
Super-tdu (1-31) TFA is an endogenous ligand of heptapeptide receptor and has a strong anti-analgesic effect.
  • $153
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CGRP II, rat (TFA) (99889-63-1 free base)
TP1201
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
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ACTH (1-14) TFA (25696-21-3 free base)
TP1237
ACTH (1-14) (TFA) is a polypeptide of corticotrophin, which promotes the release of cortisol.
  • $63
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HIF-1 alpha (556-574) TFA (1201633-99-9 free base)
TP1546
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part
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MART-1 (26-35) (human) TFA (156251-01-3 free base)
TP1462
MART-1 (26-35) (human) TFA is an amino acid residue of 26-35 protein.
  • $85
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Angiotensin I, asn(1)-val(5)-gly(9)-
TP244795211-04-4
Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
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TAT-DEF-Elk-1 TFA (1220751-16-5 free base)
TP2157L
TAT-DEF-Elk-1 TFA is a cell-penetrating peptide Elk-1 inhibitor, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 act
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Substance P(1-7) TFA
T759632828433-22-1
Substance P(1-7) TFA, a fragment of the neuropeptide substance P (SP), induces depressor and bradycardic effects upon application to the nucleus tractus solitarius [1].
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GLP-1(32-36)amide TFA
T76192
GLP-1(32-36)amide TFA, a pentapeptide derived from the C-terminal end of the glucoregulatory hormone GLP-1, has demonstrated the ability to mitigate weight gain and regulate glucose metabolism in diabetic mice [1] [2].
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Grb2 SH2 domain inhibitor 1 TFA
T77994
Grb2 SH2 Domain Inhibitor 1 TFA is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R signifies D-arginine, and P stands for D-proline. It primarily functions as a cyclic peptide inhibitor.
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Orexin B, human TFA (205640-91-1 free base)
TP1138
Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2.
  • $238
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A8SGLP-1 TFA
T80306
A8SGLP-1 TFA, an orally active GLP-1 analogue, features a serine substitution for alanine at position 8. This compound effectively lowers blood glucose in db/db mice, maintaining its function [1].
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Stressin I TFA
T81081
Stressin I (Cyclo(31-34)[DPhe12, Nle21, 38, Glu31, Lys34]Ac-hCRF(4-41)) TFA, with a K i of 1.7 nM, is a potent and selective agonist of the CRF1 receptor that elevates adrenocorticotropic hormone (ACTH) levels in rats [1].
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TAT TFA (191936-91-1 free base)
TP1407
TAT TFA (YGRKKRRQRRR) is derived from human immunodeficiency virus (hiv-1) transcription reverse activator TAT, is a cell penetrating peptide.
  • $117
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