apn peg4 amine hydrochloride

APN-PEG4-Amine (hydrochloride) is a cleavable four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Pomalidomide 4'-PEG5-amine, a cereblon ligand designed for PROTAC research and development, features an integrated E3 ligase ligand and a PEG5 linker ending in an amine for easy conjugation to target protein ligands. It is among a series of functionalized tool molecules specifically crafted for PROTAC R&D.

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

S-acetyl-PEG4-amine, a PEG-based linker for PROTACs, joins two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methyltetrazine-PEG4-amine is a polyethylene glycol (PEG) derivative serving as a PROTAC linker for the synthesis of PROTACs[1].

Methyl cis-4-Hydroxy-L-proline Hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65222 and the CAS number is 40126-30-5.

111-Trifluoroethyl-PEG4-amine is a polyethylene glycol (PEG)-based linker appropriate for synthesizing proteolysis-targeting chimeras (PROTACs) [1].

PTAD-PEG4-amine is a 4-unit cleavable polyethylene glycol (PEG) linker primarily employed in the synthesis of antibody-drug conjugates (ADCs)[1].

APN-C3-PEG4-azide is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. This linker supports selective protein degradation via the cell's ubiquitin-proteasome system.

APN-PEG4-BCN is a cleavable, four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Amine-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

BDP FL-PEG4-amine is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Lenalidomide-4-aminomethyl hydrochloride is a compound derived from Lenalidomide, serving as a cereblon (CRBN) ligand for the recruitment of CRBN protein. By connecting Lenalidomide-4-aminomethyl hydrochloride to the ligand via a linker, PROTAC formation can be facilitated.

Amine-PEG-amine (MW 20000) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs.

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG)-derived linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Azido-PEG4-4-nitrophenyl carbonate, a PEG-derived PROTAC linker, enables the synthesis of PROTACs[1].

Biotin-PEG4-amine is a biotinylated, PEGylated amine linker utilized in PROTAC synthesis[1].

trans-4-Hydroxy-D-proline hydrochloride, with catalog number T65471 and CAS number 142347-81-7, is a valuable organic compound for life sciences research.

DBCO-C3-PEG4-amine is a PEG-based linker for PROTACs that joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-4-O-C11-NH2 hydrochloride is a thalidomide-based cereblon ligand for CRBN protein recruitment, capable of conjugation to a protein ligand via a linker to create PROTACs [1].

Thalidomide-4-O-C12-NH2 hydrochloride is a cereblon ligand derived from Thalidomide, used to recruit the CRBN protein. It can be linked to a protein ligand via a linker, facilitating the creation of PROTACs [1].

APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), consisting of a four-unit PEG and a DBCO moiety, used in ADC synthesis[1].

DBCO-C2-PEG4-amine, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

N,N-Diethanolamine-PEG4-Boc is a PEG-based PROTAC linker for PROTAC synthesis [1].

HO-PEG-amine (MW 5000) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

cis-4-Hydroxy-L-proline hydrochloride [catalog number: T65954, CAS number: 441067-49-8] is a valuable organic compound for life sciences research.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Cy5-PEG5-amine (hydrochloride) is a PEG-derived PROTAC linker used in PROTAC synthesis[1].

HO-PEG-amine (MW 10000), a polyethylene glycol (PEG) derivative, is utilized as a PROTAC linker for the synthesis of PROTACs[1].

N-Mal-N-bis(PEG4-amine) is a PEG-based linker used in PROTAC synthesis [1].

DSPE-PEG-Amine (MW 3400), a polyethylene glycol (PEG)-based PROTAC linker, serves as a crucial component in the synthesis of PROTACs[1].

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].

DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].

Thalidomide-O-PEG4-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Thalidomide-4-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be conjugated with a protein ligand via a linker to synthesize PROTACs [1].

Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker used in PROTAC synthesis.