ar-m 1000390 hydrochloride

AR-M 1000390 hydrochloride (ARM-390 HCl) , also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.

AR-M 1896 Acetate is the selective agonist of GalR2.

AR-C141990 hydrochloride is a potent inhibitor of lactate transporters known as monocarboxylate transporters (MCTs). It has pK i values of 7.6 and 6.6 for MCT-1 and MCT-2, respectively. Additionally, this compound exhibits immunosuppressive properties and effectively inhibits the graft versus host response.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-morpholinoethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-heptyloxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

m-Acetotoluidide, 6'-chloro-2-(diethylamino)-alpha,alpha,alpha-trifluoro-, hydrochloride is a bioactive chemical.

Monocarboxylate transporter (MCT1) inhibitor (pKi = 7.6. Exhibits approximately 10-fold selectivity for MCT1 over MCT2 and no significant activity against MCT3 or 4. Inhibits graft versus host response and prolongs cardiac graft survival in a rat model. Immunosuppressant. Also inhibits brain penetration of GHB analog HOCPCA.

Acetamide, 2-(p-butoxyphenoxy)-N-(2-(dimethylamino)ethyl)-N-(m-ethoxyphenyl)-, hydrochloride is a bioactive chemical.

Phenol, m-(1,3-dimethyl-3-pyrrolidinyl)-, acetate, hydrochloride is a bioactive chemical.

Phenol, m-(2-(methylamino)ethyl)-, hydrochloride is a biaoctive chemical.

AR-R17779 hydrochloride is a potent, selective full agonist of the nAChR, demonstrating K i values of 92 nM for the α7 subtype and 16,000 nM for the α4β2 subtype. It is noted for its ability to enhance learning and memory in rats, suggesting potential therapeutic applications. Additionally, this compound exhibits anxiolytic properties and can mitigate inflammation by activating anti-inflammatory cholinergic (vagal) pathways [1] [2] [4].

Carbanilic acid, m-((pentyloxy)methyl)-, 2-(1-pyrrolidinyl)ethyl ester, hydrochloride is a bioactive chemical.

Carbanilic acid, m-hexyloxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-piperidinoethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-hexyloxy-, 2-(diethylamino)cyclohexyl ester, hydrochloride, (E)- is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride is a bioactive chemical.

m-Toluidine, alpha-methoxy-4-(octyloxy)-, hydrochloride is a bioactive chemcial.

Carbanilic acid, m-((pentyloxy)methyl)-, 2-(hexahydro-1H-azepin-1-yl)ethyl ester, hydrochloride is a bioactive chemical.

5-HT3 receptor agonist

m-Acetotoluidide, 4'-chloro-2-(diethylamino)-alpha,alpha,alpha-trifluoro-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-hexyloxy-, 2-piperidinocyclohexyl ester, hydrochloride, (E)- is a bioactive chemical.

Carbanilic acid, m-heptyloxy-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

m-Anisidine, 4-((3-ethylheptyl)oxy)-, hydrochloride is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(diethylamino)ethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-(hexahydro-1H-azepin-1-yl)ethyl ester, hydrochloride is a bioactive chemical.

Phenol, m-(2-(phenethylamino)ethyl)-, hydrochloride can be used in related research in the field of life sciences. Its product number is T34006 and CAS number is 70045-20-4.

Phenethyl alcohol, m-chloro-alpha-((isopropylamino)methyl)-, hydrochloride is a bioactive chemical.

Phenol, m-(1-methyl-3-propionyl-3-pyrrolidinyl)-, hydrochloride is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(dimethylamino)ethyl)-, hydrochloride is a bioactive chemical.

m-Dimethylaminomethyleneiminophenol hydrochloride is a bioactive chemical.

Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(3-(diethylamino)propyl)-, hydrochloride is a bioactive chemical.

Phenol, m-(1-(p-hydroxyphenethyl)-3-isopropyl-3-pyrrolidinyl)-, hydrochloride, hydrate is a bioactive chemical.

TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo. Zhu et al (2015) Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. Br.J.Pharmacol. 172 3495 PMID:25816897 |Yang et al (2015) Acute treatment with a novel TRPC4/C5 channel inhibitor produces antidepressant and anxiolytic-like effects in mice. PLoS One 10 e0136255 PMID:26317356

Carbanilic acid, m-((hexyloxy)methyl)-, 2-(1-pyrrolidinyl)ethyl ester, hydrochloride is a bioactive chemical.

Benzoic acid, m-hydroxy-, 3-(2-methylpiperidino)propyl ester, hydrochloride is a bioactive chemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(1-methyl-2-(1-pyrrolidinyl)ethyl)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-((pentyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

AR-C102222 hydrochloride is a competitive, orally active, and highly selective inducible nitric oxide synthase (iNOS) inhibitor (IC50: 37 nM). It has antinociception and anti-inflammatory activities.

Benzylamine, m-chloro-N-(2-chloroethyl)-N-ethyl-, hydrochloride is a bioactive chemical.

m-Toluidine, 4-(octyloxy)-alpha-(propylthio)-, hydrochloride is a bioactive chemical.

m-Anisidine, 4-((1-methylheptyl)oxy)-, hydrochloride is a bioactive chemical.

Carbanilic acid, m-ethoxy-, 2-(dimethylamino)ethyl ester, hydrochloride is a bioactive chemical.