aripiprazole

Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.

Dehydro aripiprazole is the primary, active metabolite of aripiprazole, an atypical antipsychotic. The metabolite is produced from the parent compound by the actions of cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6. Dehydro aripiprazole has similar pharmacological properties to aripiprazole.

Aripiprazole-d8 is a deuterated compound of Aripiprazole. Aripiprazole has a CAS number of 129722-12-9. Aripiprazole is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.

Dehydro aripiprazole-d8 is a deuterated compound of Dehydro aripiprazole. Dehydro aripiprazole has a CAS number of 129722-25-4. Dehydroaripiprazole is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has antipsychotic activity equivalent to aripiprazole.

Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).

Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic.

Aripiprazole (OPC-14597) monohydrate is an atypical antipsychotic that is a potent, high-affinity partial agonist of the dopamine D2 receptor.Aripiprazole monohydrate is an inverse agonist of the 5-HT2B and 5-HT2A receptors, and is active on 5-HT1A, 5-HT2C, D3 and D4. Aripiprazole monohydrate can be used to study schizophrenia and COVID19.

Aripiprazole cavoxil is used in Treatment of Schizophrenia, Bipolar Disorder, and Clinical Depression.

Dehydroaripiprazole (DM-14857) is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has antipsychotic activity equivalent to aripiprazole.