azd-co-c-2-ph-amido-ph-azide

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs [1].

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker used for PROTAC synthesis.

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate that integrates a Pomalidomide-based cereblon ligand with a 4-unit PEG linker.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker used for PROTAC synthesis [1].

Tetrazine-Ph-OPSS is an ADC linker employed for synthesizing ADCs, or antibody-drug conjugates [1].

Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG4-based linker used in PROTACs synthesis [1].

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs[1].

Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound comprising a cereblon (CRBN) ligand that functions as an E3 ubiquitin ligase, along with a linker. It is utilized to create the PROTAC MD-224[1].

Ald-Ph-PEG2-Boc is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound used in the synthesis of PROTACs [1].

Boc-Gly-amido-C-PEG3-C3-amine is a polyethylene glycol (PEG)-based PROTAC linker used in PROTAC synthesis [1].

Dox-Ph-PEG1-Cl, also referred to as PROTAC Linker 34, is a PEG-based compound employed for the synthesis of PROTACs[1].

Azide-PEG9-amido-C8-Boc is a polyethylene glycol (PEG) derived linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used in the development of antibody-drug conjugates (ADCs).

Tetrazine-Ph-PEG5-NHS ester is a PEGylated N-hydroxysuccinimide (NHS) ester molecule utilized as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Compound PA, also known as Pomalidomide-CO-C5-azide, serves as a ligand for E3 ligase and features a bioorthogonal azide group. This compound is utilized in the synthesis of PROTACs that exhibit anticancer properties [1].

Ald-Ph-amido-PEG2-C2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Mal-NO2-Ph-PEG12-NHS is a PEG-based linker for PROTACs, connecting two essential ligands for forming PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies and drugs.

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used in the development of antibody-drug conjugates (ADC).

Tetrazine-Ph-NHS ester is an alkyl ether-based PROTAC linker commonly used for synthesizing PROTACs[1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate designed for targeting the EED protein in PROTAC applications[1].

Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG23-OPSS is a cleavable, 23-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker used for synthesizing PROTAC ARD-266[1].

Ald-Ph-PEG24-TFP ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG3-C1-Boc is a polyethylene glycol (PEG) linker used specifically in antibody-drug conjugates (ADC).

PDP-C1-Ph-Val-Cit is a cleavable ADC linker used in antibody-drug conjugates (ADCs).

Ald-Ph-PEG6-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, designed for synthesizing proteolysis-targeting chimeras (PROTACs) [1].

Tetrazine-Ph-NHCO-PEG3-alcohol is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugates (ADCs)[1].

(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is an E3 ligase ligand-linker conjugate that combines a VHL ligand for the E3 ubiquitin ligase with a PROTAC linker; it is used in PROTAC EED degrader-1, targeting EED with a potency (pKD) of 9.02[1].

Azide-PEG9-amido-C16-Boc is an alkyl ether-based PROTAC linker used in PROTAC synthesis [1].