azide-peg3-sulfone-peg3-azide

Azide-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based bifunctional molecule, designed as a PROTAC linker for PROTAC synthesis [1].

m-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based linker commonly used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

Bromo-PEG1-C2-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Azido-PEG9-azide is a PEG-based PROTAC linker suitable for use in PROTAC synthesis.

Azide-PEG12-Tos is a PEG-based PROTAC linker employed in PROTAC synthesis.

Azido-PEG4-azide is a PEG-based PROTAC linker used for synthesizing PROTACs.

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Azide-PEG12-alcohol, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.

Azido-PEG5-azide, a PEG-based PROTAC linker, is used in PROTAC synthesis.

Biotin-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Azido-PEG11-azide is a PEG-based PROTAC linker used in PROTAC synthesis.

Azido-PEG1-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

Azido-PEG3-azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate, comprising a Pomalidomide-based cereblon ligand and a linker.

Biotin-PEG6-azide (Biotin-PEG6-N3) is a biotin-labeled, PEG-based PROTAC linker that can be used in PROTAC synthesis.

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Biotin-PEG3-SS-azide (Biotin-PEG3-amido-SS-amido-azide) is a cleavable ADC linker containing 3-unit PEG and can be used to synthesize antibody-drug conjugates (ADCs).

Boc-NH-PEG15-azide, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Azide-PEG9-amido-C8-Boc is a polyethylene glycol (PEG) derived linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

S-Acetyl-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis [1].

LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM for cyclin T1 and 662 nM for CDK9. This compound consists of the CDK9 inhibitor, SNS 032, linked to a hydrophobic tag via a glycol linker. Notably, LL-K9-3 does not affect the degradation of other CDKs (CDK1, 2, 4, 5, 6, and 7). Tested in 22RV1 cells, it effectively reduces androgen receptor (AR) and cMyc expression by inducing the selective and synchronous degradation of CDK9 and cyclin T1.

3-Mercaptopropionic acid NHS ester is a useful organic compound for research related to life sciences and the catalog number is T64663.

Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1].

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs [1].

N-Hydroxypropyl-N’-(azide-PEG3)-Cy3 is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Azido-PEG3-S-PEG3-azide is a polyethylene glycol (PEG)-derived linker engineered for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bromo-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

m-PEG36-azide is a PEG-based linker for PROTACs that connects two critical ligands, facilitating the formation of PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methyl 3-hydroxypropanoate is a PROTAC linker compound, which belongs to the alkyl ether family. It is commonly employed in the synthesis of PROTACs.

PROTAC BET Degrader-3 is a potent degrader of BET proteins based on the PROTAC (PROteolysis TArgeting Chimera) technology.

UAA crosslinker 2 is a phenylalanine derivative.

Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

PC-PEG11-Azide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a seven-unit polyethylene glycol (PEG) linker used in the synthetic production of antibody-drug conjugates (ADCs) and is cleavable[1].

PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].

Boc-Aminooxy-PEG4-azide, a polyethylene glycol (PEG) derived linker, has potential applications in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

m-PEG24-azide is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Lipoamido-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Aminooxy-PEG-OH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Azide-PEG3-Tos is a PEG-based PROTAC linker used in the synthesis of PROTACs[1], and a non-cleavable 3-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).