azido peg1 c2 methylamine

Azido-PEG1-C2-methylamine is a PEG-conjugated linker utilized in the synthesis of PROTACs [1].

Bromo-PEG1-C2-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Azido-PEG1-CH2CO2H, a PROTAC linker characterized by an alkyl ether combination, can be utilized to synthesize PROTAC BRD4 Degrader-1[1].

Azido-PEG1-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

Azido-PEG1-amine, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by exploiting the ubiquitin-proteasome system within cells.

Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.

Azido-PEG1-NHS ester is a PEG-based linker for PROTACs, enabling the formation of PROTAC molecules by joining two essential ligands and facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-N-PEG1-C2-NHS ester, a PEG-based linker, finds utility in PROTAC synthesis[1].

Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl ether-based linker utilized in the synthesis of PROTACs [1].

Azido-PEG3-C-Boc is a PEG-based linker for PROTACs that connects two essential ligands, crucial for the formation of PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs[1].

Azido-C2-SS-PEG2-C2-acid is a cleavable PEG linker with two units used in the synthesis of antibody-drug conjugates (ADCs) [1].

Azido-PEG1-CH2CO2-NHS is an alkyl ether-based linker utilized in the synthesis of PROTACs [1].

Boc-Aminooxy-PEG1-C2-NH2 is a polyethylene glycol (PEG)-derived linker compound designed for incorporation into proteolysis targeting chimeras (PROTACs) [1].

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Tri-(PEG1-C2-acid) is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

Azido-PEG1-Val-Cit-OH is a cleavable, one-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

DBCO-C-PEG1 is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH, a chemical compound that serves as a linker incorporating TLR4 inhibitor TLR4-IN-C34, effectively inhibits TLR4 in both enterocytes and macrophages, significantly reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

N-Boc-N-bis(C2-PEG1-azide) is an alkyl ether-based PROTAC linker suitable for synthesizing PROTACs [1].

Bromo-PEG1-C2-Boc is a PEG-based linker for PROTACs, which connects two essential ligands necessary for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-PEG1-C2-Boc is an alkyl-ether-based linker used for synthesizing PROTACs, a class of small molecules inducing targeted protein degradation [1].

Azido-PEG2-C2-acid is a PEG-based linker for PROTACs that joins two essential ligands, facilitating PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG1-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system in cells.

Acid-PEG1-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Amino-PEG1-C2-acid is a PEG-based linker used in PROTACs to conjugate two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Hydroxy-PEG1-C2-methyl ester, a polyethylene glycol (PEG) derived linker, is widely used in the production of PROTACs (proteolysis targeting chimeras). [1]

Mal-amido-PEG1-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that incorporates a maleimide functional group and an N-hydroxysuccinimide (NHS) ester. The NHS ester offers a means to specifically modify primary amines (-NH2) present in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) is a PEG-based linker suitable for the synthesis of PROTACs, which are compound complexes designed to selectively degrade target proteins[1].

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Pomalidomide-PEG1-C2-N3, a conjugate of an E3 ligase ligand-linker, incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, commonly used in PROTAC technology. This compound enables the design of the selective CDK6 PROTAC degrader CP-10, which effectively induces CDK6 degradation with a DC50 value of 2.1 nM[1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].

Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a chemical linker with the TLR4 inhibitor TLR4-IN-C34, which inhibits TLR4 in enterocytes and macrophages, reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].

Amino-PEG3-C2-Azido, a polyethylene glycol (PEG)-based linker, is utilized in synthesizing iRucaparib-TP3, a PARP1 degrader [1].

Azido-PEG1-C1-Boc is an alkyl ether-based PROTAC linker employed in PROTAC synthesis[1].

Azido-PEG6-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

C-NH-Boc-C-Bis-(C-PEG1-Boc) is a versatile alkyl ether-based PROTAC linker used for synthesizing PROTACs [1].

Azido-PEG2-C2-sulfonic acid is a polyethylene glycol (PEG) derived linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in the synthesis of PROTACs[1].

m-PEG3-S-PEG1-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl ether-based PROTAC linker commonly used in the synthesis of PROTAC BRD4 Degrader-1[1].

Azido-PEG8-C-Boc is a PEG-based linker for PROTACs that connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable one-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].